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Documentos Principais

B1141000

Bleomycin sulfate

European Pharmacopoeia (EP) Reference Standard

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
41116107
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

pharmaceutical primary standard

família API

bleomycin

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[S+](CCCNC(=O)c1nc([s]c1)c2nc([s]c2)CCNC(=O)C(NC(=O)C(C(O)C(NC(=O)C(NC(=O)c6nc(nc(c6C)N)C(NCC(N)C(=O)N)CC(=O)N)C(O[C@@H]4O[C@H]([C@H]([C@@H]([C@@H]4O[C@H]5O[C@@H]([C@H]([C@@H]([C@@H]5O)O\C(=N\[H])\[O-])O)CO)O)O)CO)c3[nH]cnc3)C)C)C(O)C)(C)C.[S](=O)(=O)(O)O

InChI

1S/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/t21?,22?,23?,24?,25?,29-,30+,34?,35?,36?,37+,38+,39-,40-,41?,42-,43-,53+,54-;/m0./s1

chave InChI

WUIABRMSWOKTOF-OCBSMOPSSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Bleomycin sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Carc. 2 - Muta. 1B - Repr. 2

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Idiopathic pulmonary fibrosis has been associated with the reactivation of developmental pathways, notably the Hedgehog-Glioma-associated oncogene homolog (GLI) pathway. In this study, we determined whether the Hedgehog pathway was activated in bleomycin-induced lung injury in mice, and whether targeting the
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Questions

1–2 of 2 Questions  
  1. We bought Bleomycin sulfate (B1141000). Can we convert it from mg to unit?

    1 answer
    1. This is a product of the European Pharmacopoeia. The activity is reported in the supplier Leaflet. The current shipping lot has an activity of 14,015 IU per 7 mg vial. Please see the link below to review the supplier product page:
      https://crs.edqm.eu/db/4DCGI/View=B1141000

      Helpful?

  2. bonjour, quelle quantité de bléomycine il y a t'il dans un lot ?

    1 answer
    1. This is a product of the European Pharmacopoeia. Batch sizes for this material are not reported. The product is offered in a 7mg package size.

      Please see the link below for more information:
      https://crs.edqm.eu/db/4DCGI/search?vSelectName=2&vContains=1&vtUserName=B1141000&OK=Search&vTypeCRS=

      Helpful?

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