A9797

Ambroxol hydrochloride

analytical standard

• Sinônimo(s): 2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
• Fórmula empírica (Notação de Hill): C₁₃H₁₈Br₂N₂O · HCl
• Número CAS: 23828-92-4
• Peso molecular: 414.56
• Número CE: 245-899-2
• Número MDL: MFCD00078932
• Código UNSPSC: 41116107
• ID de substância PubChem: 329771060
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• prazo de validade: limited shelf life, expiry date on the label
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
• InChI: 1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
• chave InChI: QNVKOSLOVOTXKF-PFWPSKEQSA-N

Descrição

Descrição geral

Ambroxol hydrochloride is a mucolytic expectorant and a metabolite of bromhexine.[1][2] It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.[3]

Aplicação

Ambroxol hydrochloride standard may be used as a reference standard in the determination of ambroxol hydrochloride in pharmaceutical preparations using reversed-phase sequential injection chromatography (RP-SIC)[1] and reversed-phase high performance liquid chromatography (RP-HPLC).[2]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Metabolite of bromhexine.
A Nav1.8-preferring sodium channel blocker

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves