A4673

Albendazole

analytical standard, ≥98%

• Sinônimo(s): Methyl 5-(propylthio)-2-benzimidazolecarbamate
• Fórmula empírica (Notação de Hill): C₁₂H₁₅N₃O₂S
• Número CAS: 54965-21-8
• Peso molecular: 265.33
• Número CE: 259-414-7
• Número MDL: MFCD00083232
• Código UNSPSC: 41116107
• ID de substância PubChem: 329770859
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• Ensaio: ≥98%
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): forensics and toxicology; pharmaceutical (small molecule)
• Formato: neat
• cadeia de caracteres SMILES: CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
• InChI: 1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
• chave InChI: HXHWSAZORRCQMX-UHFFFAOYSA-N

Descrição

Descrição geral

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Chemical structure: benzimidazole

Aplicação

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Binds to tubulin and inhibits microtubule assembly.

Informações de segurança

• Pictogramas: GHS08,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H361d,H373,H410
• Declarações de precaução: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
• Órgãos-alvo: Adrenal gland,Blood,male reproductive organs,spleen
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)