Pular para o conteúdo
Merck
Todas as fotos(2)

Documentos

93813

Supelco

Cyclophosphamide monohydrate

analytical standard

Sinônimo(s):

2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(2)

About This Item

Fórmula empírica (Notação de Hill):
C7H15Cl2N2O2P · H2O
Número CAS:
6055-19-2
Peso molecular:
279.10
Beilstein:
4678992
Número CE:
200-015-4
Número MDL:
MFCD00149395
Código UNSPSC:
41116107
ID de substância PubChem:
329770272
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

Ensaio

≥98.0% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

Impurezas

6.45% water (theory, monohydrate)

pf

47-52 °C
49-51 °C (lit.)

aplicação(ões)

forensics and toxicology
veterinary

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

chave InChI

PWOQRKCAHTVFLB-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Frases de perigo

H301,H340,H350,H360FD

Classificações de perigo

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number
BCCJ5425
BCCG4445
BCCB7788
BCBT1588
BCBM8984V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 2

1 of 2

Fludarabine phosphate

Sigma-Aldrich

F9813

Fludarabine phosphate

Azathioprine ≥98%

Sigma-Aldrich

A4638

Azathioprine

Ji-Young Lee et al.
Chemosphere, 268, 128817-128817 (2020-11-10)
Cyclophosphamide (CP) is a widely used anticancer drug and an immunosuppressant. Since CP is nonbiodegradable, it is hardly removed by the conventional wastewater treatment processes, resulting in continuous detection in surface water. In this study, the degradation of CP during
Feng Zhao et al.
Pharmaceutical biology, 52(7), 797-803 (2014-01-08)
The in vitro and in vivo antitumor activities of ardisiphenol D, a natural product isolated from the roots of Ardisa brevicaulis Diels (Myrsinaceae), have been studied. Previously, we have isolated and identified some chemical constituents from this plant. Furthermore, these
Masahiro Murakami-Nakayama et al.
Journal of pharmacological sciences, 127(2), 223-228 (2015-03-03)
Cav3.2 T-type Ca(2+) channels targeted by H2S, a gasotransmitter, participate in cyclophosphamide-induced cystitis and bladder pain. Given that zinc selectively inhibits Cav3.2 among T-channel isoforms and also exhibits antioxidant activity, we examined whether polaprezinc (zinc-l-carnosine), a medicine for peptic ulcer
Yue Jia et al.
Apoptosis : an international journal on programmed cell death, 20(4), 551-561 (2015-02-11)
Human (HN) prevents stress-induced apoptosis in many cells/tissues. In this study we showed that HN ameliorated chemotherapy [cyclophosphamide (CP) and Doxorubicin (DOX)]-induced male germ cell apoptosis both ex vivo in seminiferous tubule cultures and in vivo in the testis. HN
Lamprini Skriapa et al.
Journal of neuroimmunology, 276(1-2), 150-158 (2014-09-30)
Antibodies against MuSK seem to be the pathogenic factor in approximately 5-8% of myasthenia gravis (MG) patients. We aim to develop an antigen-specific therapy in which only MuSK antibodies will be removed from patients' plasma using MuSK extracellular domain (MuSK-ECD)
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica