78645

Levetiracetam

analytical standard

• Sinônimo(s): (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetamide, 2(S)-(2-Oxopyrrolidin-1-yl)butyramide
• Fórmula empírica (Notação de Hill): C₈H₁₄N₂O₂
• Número CAS: 102767-28-2
• Peso molecular: 170.21
• Número MDL: MFCD03265610
• Código UNSPSC: 41116107
• ID de substância PubChem: 329768167
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• Ensaio: ≥98.0% (HPLC)
• atividade óptica: [α]/D -90±5°, c = 1 in acetone
• prazo de validade: limited shelf life, expiry date on the label
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): forensics and toxicology; veterinary
• Formato: neat
• cadeia de caracteres SMILES: CC[C@H](N1CCCC1=O)C(N)=O
• InChI: 1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1
• chave InChI: HPHUVLMMVZITSG-LURJTMIESA-N
• Informações sobre genes: human ... CACNA1B(774) , SV2A(9900)

Descrição

Descrição geral

Levetiracetam is an orally active antiepileptic drug, having a high therapeutic index and potential antiepileptogenic and anticonvulsant effects.[1][2]

Aplicação

Levetiracetam may be used as a reference standard in the determination of levetiracetam in biological fluid samples using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry (HPLC-ESI-MS/MS).[3]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Levetiracetam is a pyrrolidine with antiepileptic activity.

Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.

Produtos recomendados

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Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable