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Supelco

Diosmin

analytical standard

Sinônimo(s):

3′,5,7-Trihydroxy-4′-methoxyflavone 7-rutinoside, Barosmin, Buchu resin, Diosmetin 7-O-rhamnosylglucoside, Diosmetin 7-rutinoside

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50 MG
R$ 1.736,00

R$ 1.736,00

Previsão de entrega em31 de maio de 2025

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50 MG
R$ 1.736,00

About This Item

Fórmula empírica (Notação de Hill):
C28H32O15
Número CAS:
520-27-4
Peso molecular:
608.54
Número CE:
208-289-7
Número MDL:
MFCD00009772
Código UNSPSC:
85151701
ID de substância PubChem:
329759466
NACRES:
NA.24

R$ 1.736,00

Previsão de entrega em31 de maio de 2025

Solicite uma grande encomenda

grau

analytical standard

Nível de qualidade

100

Ensaio

≥90% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

Impurezas

≤10% water

aplicação(ões)

food and beverages

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2

InChI

1S/C28H32O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-8,10,19,21-30,32-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

chave InChI

GZSOSUNBTXMUFQ-YFAPSIMESA-N

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Descrição geral

Diosmin is a flavonoid glycoside that occurs naturally as an active constituent of citrus fruits.(1) It possess a wide range of pharmacological properties like antioxidant, anticarcinogenic, blood-lipid lowering and also anti-inflammatory activities.[1] Diosmin can also find applications in the healing of venous ulcers, enhancement of microcirculation and improvement of venous tone.[1]

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

Citrus flavonoid. Modification of hesperidin. Studied for its chemopreventive properties, including anti-proliferative and anti-inflammatory.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

This compound is commonly found in plants of the genus: mentha

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCN0895
BCCM0527
BCCH5536
BCCH6246
BCCC6711

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Hesperidin European Pharmacopoeia (EP) Reference Standard

Y0001203

Hesperidin

Orientin ≥97% (HPLC)

Sigma-Aldrich

O9765

Orientin

Ácido clorogênico European Pharmacopoeia (EP) Reference Standard

Y0000569

Ácido clorogênico

Mir Tahir et al.
Alcohol (Fayetteville, N.Y.), 47(2), 131-139 (2013-02-20)
The present investigation was designed to evaluate the efficacy of diosmin against ethanol-induced hepatotoxicity in rats by modulating various mechanisms including ethanol metabolizing enzymes, generation of free radicals, imbalance in oxidant-antioxidant status, oxidative damage to membrane lipids, activation of transcription
Jacqueline M Cohen et al.
Chest, 141(2), 308-320 (2012-02-09)
Postthrombotic syndrome (PTS) is a frequent, chronic complication of DVT. The effectiveness and safety of available treatments are unknown. The objective of this study was to systematically review the literature to assess whether pharmacologic and compression therapies are effective and
Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations
Kanaze IF, et al.
Journal of Pharmaceutical and Biomedical Analysis, 33, 243-249 (2003)
M Alcaraz et al.
Dento maxillo facial radiology, 40(5), 310-314 (2011-06-24)
The aim of this study was to evaluate the antioxidant substances present in the human diet with an antimutagenic protective capacity against genotoxic damage induced by exposure to X-rays in an attempt to reduce biological damage to as low a
Thangarasu Silambarasan et al.
European journal of pharmacology, 679(1-3), 81-89 (2012-01-24)
The present study was aimed to evaluate the antihypertensive effect of diosmin in deoxycorticosterone acetate (DOCA)-salt induced hypertension in male Wistar rats. Hypertension was induced in uninephrectomized rats by weekly twice subcutaneous injection of DOCA (25 mg/kg body weight) and
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