The solution stability has not been tested. However, literature research suggests that enrofloxacin solutions dissolved in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO) stored under frozen conditions can typically remain stable for approximately 26 to 52 weeks (6 to 12 months). The exact stability can depend on factors such as concentration, formulation, and specific storage conditions.
17849
Enrofloxacin
≥99.0%
Sinônimo(s):
Baytril
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5 G
R$ 1.019,00
25 G
R$ 3.993,00
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5 G
R$ 1.019,00
25 G
R$ 3.993,00
About This Item
Fórmula empírica (Notação de Hill):
C19H22FN3O3
Número CAS:
Peso molecular:
359.39
Beilstein:
5307824
Número MDL:
Código UNSPSC:
41116105
ID de substância PubChem:
NACRES:
NA.21
Produtos recomendados
Nível de qualidade
Ensaio
≥99.0%
99.0-101.0% (dried substance)
Formulário
powder or crystals
espectro de atividade do antibiótico
Gram-negative bacteria
Gram-positive bacteria
Modo de ação
DNA synthesis | interferes
enzyme | inhibits
cadeia de caracteres SMILES
CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4
InChI
1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
chave InChI
SPFYMRJSYKOXGV-UHFFFAOYSA-N
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Categorias relacionadas
Descrição geral
Chemical structure: fluoroquinolone
Enrofloxacin is a veterinary fluoroquinolone (FQ) antibiotic with broad-spectrum antimicrobial activity. FQ drugs chelate to iron with high affinity. This chelation leads to inhibition of Fe(II)-dependent dioxygenases involved in the regulation of epigenetic control, collagen maturation, and HIF (hypoxia-inducible factor) degradation. The side effects associated with FQ drugs are renal toxicity and tendinopathy. Enrofloxacin is used in aquaculture and its use may cause an increase in the growth of antibiotic resistant microbes in an aquatic environment. The drug may have negative effects on public health and environment.[1][2][3]
Aplicação
Enrofloxacin has been used:
- to investigate the pathological mechanisms resulting from the toxicity of fluoroquinolones in mammalian cells[1]
- to prepare a standard solution with 50% acetonitrile in a study to analyze illegal fish drugs used in aquaculture by employing surface-enhanced Raman spectroscopy (SERS)[2]
- as an analyte in a chemiluminescence reagent system[4]
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Is it possible to store the drug frozen for long-term preservation after dissolving it in organic solvents?
1 answer-
Helpful?
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What is the solubility of Antibiotic Question 17849 in water? This is intended for use in a mouse experiment involving drinking water.
1 answer-
The substance is not soluble in water. It has a solubility of 1mg/ml in organic solvents such as DMSO and 10 mg/ml in DMF. Additionally, it is suggested to try if the drug dissolves in (2-Hydroxypropyl)-β-cyclodextrin solution H5784.
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