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Documentos Principais

28-4840

Sigma-Aldrich

Sorbitan monooleate

SAJ first grade

Sinônimo(s):

Span® 80

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About This Item

Fórmula empírica (Notação de Hill):
C24H44O6
Número CAS:
Peso molecular:
428.60
Beilstein:
8172514
Número MDL:
Código UNSPSC:
12352108
ID de substância PubChem:
grau:
SAJ first grade

grau

SAJ first grade

Formulário

liquid

disponibilidade

available only in Japan

índice de refração

n20/D 1.48 (lit.)

densidade

0.986 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

[H][C@@](O)(COC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

chave InChI

NWGKJDSIEKMTRX-AAZCQSIUSA-N

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Informações legais

Span is a registered trademark of Croda International PLC

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

485.6 °F

Ponto de fulgor (°C)

252 °C


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Hoang Hirschberg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(1-2), 1-7 (2012-02-15)
In the search for an optimal approach for the transcutaneous immunization (TCI) of hepatitis B surface antigen (HBsAg), two vesicle formulations, L595 vesicles (composed of sucrose-laurate ester and octaoxyethylene-laurate ester) and sPC vesicles (composed of soybean-phosphatidylcholine and Span-80) were prepared
Faiyaz Shakeel et al.
Drug development and industrial pharmacy, 40(9), 1240-1245 (2013-07-11)
Abstract For the development of an effective self-nanoemulsifying drug delivery system (SNEDDS) of poorly soluble drugs, the knowledge of the solubility in its oil phase and SNEDDS are one of the most important factors to avoid possibility of drug to
Daniela S Bernardi et al.
Journal of nanobiotechnology, 9, 44-44 (2011-09-29)
Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing products and in treatments for skin diseases. The aim of this
Keita Hayashi et al.
International journal of biological sciences, 9(2), 142-148 (2013-02-16)
Span 80 (sorbitan monooleate) vesicles behaved differently from conventional phospholipid vesicles (liposomes) because the former had a more fluid interface. After doxorubicin hydrochloride (DOX) was encapsulated into the Span 80 vesicle (loading efficiency: 63 %), DOX-loaded Span 80 vesicles (DVs)
Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 106, 258-264 (2013-02-26)
We have focused on the interaction between the Span 80 vesicle and phospholipid vesicle (liposome). The Span 80 vesicle was mixed with a phospholipid vesicle (liposome), used as a simplified model of plasma membrane. From calcein leakage experiments, it was

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