10127647001

Glucose-6-phosphate

mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

• Sinônimo(s): D-Glucose 6-phosphate disodium salt hydrate, G-6-P-Na₂, Robison ester
• Fórmula empírica (Notação de Hill): C₆H₁₁Na₂O₉P · xH₂O
• Número CAS: 3671-99-6
• Peso molecular: 304.10 (anhydrous basis)
• Beilstein: 5199009
• Número MDL: MFCD00150940
• Código UNSPSC: 12352302
• ID de substância PubChem: 329748950

Propriedades

• Formulário: solid
• peso molecular: (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
• embalagem: pkg of 5 g
• fabricante/nome comercial: Roche
• Condições de expedição: ambient
• cadeia de caracteres SMILES: O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
• InChI: 1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
• chave InChI: UUWJZXLTPORJKW-WYFATIGWSA-L

Descrição

Descrição geral

Disodium salt

Aplicação

Substrate for glucose-6-phosphatase.

Ações bioquímicas/fisiológicas

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway.[1] Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.[2]

Qualidade

Contaminants: <0.2% glucose (enzymatic)

Variante da fórmula

C₆H₁₁O₉PNa₂

Nota de preparo

77% glucose-6-P (enzymatic), 13% sodium, 8% water

Outras notas

For life science research only. Not for use in diagnostic procedures.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): does not flash
• Ponto de fulgor (°C): does not flash