MADKMAG-71K
MILLIPLEX® Mouse Adipokine Magnetic Bead Panel - Endocrine Multiplex Assay
The analytes available for this multiplex kit are: IL-6, Insulin, Leptin, MCP-1, PAI-1 (Total), Resistin, TNF-α.
Sinônimo(s):
luminex mouse adipokine multiplex kit, luminex mouse obesity multiplex kit, millipore mouse metabolic syndrome disease multiplex, mouse metabolism diabetes immunoassay panel
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About This Item
Código UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
Produtos recomendados
Nível de qualidade
reatividade de espécies
mouse
fabricante/nome comercial
Milliplex®
assay range
accuracy: 77-92%
standard curve range: 12.2-50,000 pg/mL
técnica(s)
multiplexing: suitable
método de detecção
fluorometric (Luminex xMAP)
Condições de expedição
wet ice
Descrição geral
The discovery of leptin secretion from adipocytes in 1994 led to the recognition that white adipose tissue is involved in a variety of metabolic and physiological processes. Adipocytes secrete several hormones called adipokines with functions that include appetite and energy balance, insulin sensitivity and lipid metabolism.
MILLIPLEX® Mouse Adipokine Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in mouse serum and plasma samples: IL-6, Insulin, Leptin, MCP-1, PAI-1 Total, Resistin and TNFα. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Metabolism
MILLIPLEX® Mouse Adipokine Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in mouse serum and plasma samples: IL-6, Insulin, Leptin, MCP-1, PAI-1 Total, Resistin and TNFα. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Metabolism
Especificidade
Cross Reactivty
Each antibody pair in a panel is highly specific and displays insignificant cross-reactivity to other analytes in the panel.
Each antibody pair in a panel is highly specific and displays insignificant cross-reactivity to other analytes in the panel.
Aplicação
- Analytes: IL-6, Insulin, Leptin, MCP-1 (CCL2), PAI-1 (Total), Resistin, TNF-α
- Recommended Sample Type: Mouse serum and plasma
- Recommended Sample Dilution: 10 μL per well of undilute d serum or plasma
- Assay Run Time: Overnight (16-18 hours) at 2-8°C.
- Research Category: Metabolism
- Research Subcategory: Endocrine, Obesity, Metabolic Disorders
Características e benefícios
Design your multiplex kit by choosing available analytes within this panel.
Outras notas
Sensitivity: Please see kit protocol for sensitive’s of individual biomarkers.
Informações legais
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
Código de classe de armazenamento
10 - Combustible liquids
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Dimiter Avtanski et al.
Animal models and experimental medicine, 2(4), 252-258 (2020-01-17)
Animal models of diet-induced obesity (DIO) are commonly used in medical research for mimicking human diseases. There is no universal animal model, and careful evaluation of variety of factors needs to be considered when designing new experiments. Here, we investigated
Linda A Toth et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 54(6), 708-717 (2015-12-04)
To determine how housing density and ambient temperature interact to influence the physiology and behavior of mice, we systematically varied housing density (1 to 5 mice per cage) and ambient temperature (22, 26, or 30 °C) and measured effects on
Sara A DiVall et al.
PloS one, 10(3), e0119995-e0119995 (2015-03-18)
Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gonadotropin-releasing
Brandon D Kayser et al.
PloS one, 10(3), e0121954-e0121954 (2015-04-04)
Obesity causes white adipose tissue (WAT) inflammation and insulin resistance in some, but not all individuals. Here, we used a mouse model of early postnatal overfeeding to determine the role of neonatal nutrition in lifelong WAT inflammation and metabolic dysfunction.
Salman Azhar et al.
Molecular and cellular endocrinology, 480, 1-11 (2018-10-06)
Previously, apoE-derived ABCA1 agonist peptides have been shown to possess anti-atherosclerotic and possibly antidiabetic properties. Here we assessed the in vitro and in vivo actions of a second generation of ABCA1 peptide agonists, CS6253 and T6991-2, on glucose homeostasis. The
Conteúdo relacionado
Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.
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