MAB5216
Anti-NMDAR2A Antibody
Chemicon®, from mouse
Sinônimo(s):
NR2A
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
forma do anticorpo
affinity purified immunoglobulin
clone
monoclonal
reatividade de espécies
human
fabricante/nome comercial
Chemicon®
técnica(s)
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
Isotipo
IgG1
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... GRIN2A(2903)
Imunogênio
Amino acid region 1099-1213 from human NMDAR2A produced as a GST fusion protein.
Aplicação
Anti-NMDAR2A Antibody detects level of NMDAR2A & has been published & validated for use in IH(P), IC, IH & WB.
Immunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue: 2.5-5 μg/mL.
Immunocytochemistry: 2.5-5.0μg/mL
Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
Immunocytochemistry: 2.5-5.0μg/mL
Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Ligação
Replaces: MAB5218
forma física
Affinity purified immunoglobulin. Liquid in PBS. Contains no preservative.
Format: Purified
Armazenamento e estabilidade
Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
recomendado
Nº do produto
Descrição
Preços
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
nwg
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Regulation of NMDA receptors by cyclin-dependent kinase-5.
Li, BS; Sun, MK; Zhang, L; Takahashi, S; Ma, W; Vinade, L; Kulkarni, AB; Brady, RO; Pant, HC
Proceedings of the National Academy of Sciences of the USA null
Andre Fischer et al.
Neuron, 48(5), 825-838 (2005-12-13)
While deregulation of cyclin-dependent kinase 5 (Cdk5) has been implicated in neurodegenerative diseases, its precise role in synaptic plasticity and memory remains elusive. Proteolytic cleavage of p35, a regulatory subunit of Cdk5, by calpain results in the generation of the
Young-A Lee et al.
The European journal of neuroscience, 34(3), 426-436 (2011-06-23)
Chronic stress causes various detrimental effects including cognitive and affective dysfunctions. Given the recent findings emphasizing the importance of information processing between the prefrontal cortex (PFC) and limbic structures on cognitive and affective functions, impairments of these functions caused by
Qifa Li et al.
Frontiers in molecular neuroscience, 12, 26-26 (2019-03-12)
Chondroitin sulfate (CS) and dermatan sulfate (DS) proteoglycans (PGs) are major extracellular matrix (ECM) components of the central nervous system (CNS). A large body of evidence has shown that CSPGs/DSPGs play critical roles in neuronal growth, axon guidance, and plasticity
Ruifa Mi et al.
Neuron, 44(2), 335-349 (2004-10-12)
Under standard conditions, cultured ventral spinal neurons cluster AMPA- but not NMDA-type glutamate receptors at excitatory synapses on their dendritic shafts in spite of abundant expression of the ubiquitous NMDA receptor subunit NR1. We demonstrate here that the NMDA receptor
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