TRP (transient receptor potential)-related ion channels (TRPCs) have been postulated as candidates for forming both receptor-operated (ROCE) and capacitative Ca2+ entry channels across the plasma membrane. ER transmembrane protein STIM1 senses the depletion of Ca2+ from ER stores. Orai proteins, interacting with TRPCs, act as regulatory subunits that confers STIM1-mediated store depletion sensitivity to these channels and regulate Ca2+ influx through the plasma membrane.
Especificidade
Catalogue No. AB9870 recognizes the C-Terminus of STIM1.
Imunogênio
Synthetic Linear Peptide
Aplicação
Anti-STIM1 Antibody is an antibody against STIM1 for use in WB.
Optimal working dilutions must be determined by the end user.
Research Category Neuroscience
Research Sub Category Ion Channels & Transporters
Qualidade
Routinely evaluated in western blotting using Jurkat lysate.
Descrição-alvo
80 kDa
forma física
Format: Purified
Protein A purified
Purified in PBS with 0.05% NaN3
Armazenamento e estabilidade
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Nota de análise
Control Jurkat lysate.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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