8.52419

Fmoc-Cys(THP)-OH

Novabiochem^®

• Sinônimo(s): Fmoc-Cys(THP)-OH, N-α-Fmoc-S-(tetrahydropyranyl)-L-cysteine
• Fórmula empírica (Notação de Hill): C₂₃H₂₅NO₅S
• Número CAS: 1673576-83-4
• Peso molecular: 427.51
• Código UNSPSC: 12352209

Propriedades

• Nível de qualidade: 200
• linha de produto: Novabiochem^®
• forma: powder
• adequação da reação: reaction type: Fmoc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• aplicação(ões): peptide synthesis
• grupo funcional: thiol
• temperatura de armazenamento: 15-25°C

Descrição

Descrição geral

Fmoc-Cys(Thp)-OH is a new building block for Fmoc SPPS, in which the sulfhydryl group is protected with the acid-cleavable tetrahydropyranyl (Thp) group ^[1]. The use of Fmoc-Cys(Thp)-OH has been shown to give superior results to the corresponding S-Trt, S-Dpm, S-Acm, and S-StBu derivatives.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Cysteine-Containing Peptides

Nota de análise

Colour (visual): white to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informações legais

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable