8.22324

1,2-Propanediol

EMPLURA^®

• Sinônimo(s): 1,2-Propanediol, 1,2-Propylene glycol
• Fórmula linear: CH₃CH(OH)CH₂OH
• Número CAS: 57-55-6
• Peso molecular: 76.09
• Número MDL: MFCD00064272
• Código UNSPSC: 12352104
• Número do índice EC: 200-338-0
• NACRES: NB.21

Propriedades

• pressão de vapor: 0.11 hPa ( 20 °C)
• Nível de qualidade: 200
• linha de produto: EMPLURA^®
• Ensaio: ≥99% (GC)
• Formulário: liquid
• temperatura de autoignição: 371 °C
• potência: 19400-36000 mg/kg LD₅₀, oral (Rat); 20800 mg/kg LD₅₀, skin (Rabbit)
• Lim. expl.: 2.4-17.4 % (v/v)
• dilution: (low-cost alternative, for basic applications)
• Impurezas: ≤0.2% Water
• índice de refração: n20/D 1.43
• pH: 6-8 (20 °C, 100 g/L in H₂O)
• p.e.: 188 °C/1013 hPa
• pf: -59 °C
• temperatura de transição: flash point 99 °C
• densidade: 1.04 g/cm³ at 20 °C
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: OC(CO)C
• InChI: 1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
• chave InChI: DNIAPMSPPWPWGF-UHFFFAOYSA-N

Descrição

Aplicação

• (1)H-NMR metabolomics investigation of CSF from children with HIV reveals altered neuroenergetics due to persistent immune activation.: This research uses 1,2-Propanediol in metabolic profiling to study CSF in children with HIV, identifying neuroenergetic alterations due to persistent immune activation (Thirion et al., 2024).


• Insight into the influence of natural deep eutectic solvents on the extraction of phenolic compounds from poplar type propolis: Composition and in vitro biological activity.: The study explores using 1,2-Propanediol-based deep eutectic solvents for extracting phenolic compounds from propolis, assessing their composition and biological activity (Trusheva et al., 2024).


• In Silico-Assisted Isolation of trans-Resveratrol and trans-e-Viniferin from Grapevine Canes and Their Sustainable Extraction Using Natural Deep Eutectic Solvents (NADES).: This publication discusses the application of 1,2-Propanediol in the green chemistry extraction of valuable compounds from grapevines using computational and experimental methods (Kiene et al., 2023).


• Untargeted metabolomics provide new insights into the implication of Lactobacillus helveticus strains isolated from natural whey starter in methylglyoxal-mediated browning.: Research utilizing 1,2-Propanediol in metabolomic studies to understand the metabolic pathways influenced by Lactobacillus strains in dairy products (Galimberti et al., 2023).


• Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in conventionally colonized mice.: A study focusing on the role of 1,2-Propanediol in modulating microbial metabolites through synbiotic treatments, impacting gut microbiota and systemic health (Larke et al., 2023).

Nota de análise

Purity (GC): ≥ 99.0 %
Identity (IR): conforms
Density (d 20 °C/ 4 °C): 1.036 - 1.037
Water: ≤ 0.20 %

Informações legais

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 219.2 °F - closed cup
• Ponto de fulgor (°C): 104 °C - closed cup