8.07491

Poli(etilenoglicol)

6000, for synthesis

• Sinônimo(s): PEG
• Fórmula linear: H(OCH₂CH₂)_nOH
• Número CAS: 25322-68-3
• Número MDL: MFCD00081839
• Código UNSPSC: 13111021
• Número do índice EC: 500-038-2
• NACRES: NA.22

Propriedades

• pressão de vapor: <0.01 hPa ( 20 °C)
• Nível de qualidade: 200
• forma: solid
• temperatura de autoignição: 420 °C
• potência: 28000 mg/kg LD₅₀, oral (Rat); >20000 mg/kg LD₅₀, skin (Rabbit)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• pf: 58-63 °C
• temperatura de transição: flash point 270 °C
• densidade: 1.2 g/cm³ at 20 °C
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• chave InChI: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Descrição

Descrição geral

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels, etc. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Aplicação

Polyethylene glycol 6000 is a non-ionic surfactant that can be used as a structure-directing agent to prepare mesoporous γ-A_l2O₃. PEG 6000 induced the formation of the lamellate structure morphology of boehmite nanoparticles with improved textural properties such as high surface area, larger pore volume, and pore size. It is also used in drug formulations to enhance the dissolution rate of the poorly water-soluble drug molecule. PEG-6000 can also be used in the purification of nucleic acids via the selective precipitation method. This approach is economically cost-effective and faster than the commonly employed chromatographic purification method.

Nota de análise

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 16 - 23
Average molecular mass: 5000 - 7000
Identity (IR): passes test

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 281.5 °F - closed cup
• Ponto de fulgor (°C): 138.6 °C - closed cup