580553

(±)-Taxifolin hydrate

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M⁻¹ s⁻¹) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

• Sinônimo(s): 3,3′,4′,5,7-Pentahydroxydihydroflavone Hydrate, Dihydroquercetin Hydrate, 3,3′,4′,5,7-Pentahydroxyflavanone hydrate, Dihydroquercetin hydrate
• Fórmula empírica (Notação de Hill): C₁₅H₁₂O₇ · xH₂O
• Número CAS: 24198-97-8
• Peso molecular: 304.25 (anhydrous basis)
• Número MDL: MFCD11044454
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: white to off-white
• solubilidade: ethanol: 20 mg/mL
• Condições de expedição: ambient
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
• InChI: 1S/C15H12O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,14-19,21H;1H2/t14-,15+;/m0./s1
• chave InChI: DNQPGSVMBPSRIR-LDXVYITESA-N

Descrição

Descrição geral

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M^-1 s^-1) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

An antioxidant flavonoid that suppresses the cytotoxicity of superoxide ions and hydrogen peroxide in Chinese hamster V79 cells.

Ações bioquímicas/fisiológicas

Cell permeable: no

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Primary Target
An antioxidant flavonoid that scavenges superoxide

Product does not compete with ATP.

Reversible: no

Embalagem

Packaged under inert gas

Advertência

Toxicity: Harmful (C)

Outras notas

Kostyuk, V.A., et al. 1998. Arch. Biochem. Biophys. 355, 43.
Bors, W., et al. 1995. Free Radic. Biol. Med. 19, 45.
Nakayama, T., et al. 1994. Cancer Res. 54, 1991s.
Nakayama, T., et al. 1993. Biochem. Pharmacol. 45, 265.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable