344911

Fura-2 LR/AM

Acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound.

• Sinônimo(s): Fura-2 LR/AM, Fura-2 Leakage Resistant (AM)
• Fórmula empírica (Notação de Hill): C₅₅H₆₃N₅O₂₉
• Número CAS: 172890-84-5
• Peso molecular: 1258.10
• Número MDL: MFCD00285848
• Código UNSPSC: 12171500
• NACRES: NA.25

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (HPLC)
• Formulário: gum
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: light yellow
• solubilidade: DMSO: 10 mg/mL
• fluorescência: λ_ex 368 nm (low); λ_ex 374 nm (high); λ_em 518 nm (low); λ_em 524 nm (high)
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: N1(CCN(CC1)C(=O)CCc2cc(c(cc2)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOc3cc4c([o]c(c4)c5ncc([o]5)C(=O)OCOC(=O)C)cc3N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
• InChI: 1S/C55H63N5O29/c1-33(61)76-27-82-49(68)22-57-11-13-58(14-12-57)48(67)10-8-39-7-9-41(59(23-50(69)83-28-77-34(2)62)24-51(70)84-29-78-35(3)63)44(17-39)74-15-16-75-45-18-40-19-46(54-56-21-47(89-54)55(73)87-32-81-38(6)66)88-43(40)20-42(45)60(25-52(71)85-30-79-36(4)64)26-53(72)86-31-80-37(5)65/h7,9,17-21H,8,10-16,22-32H2,1-6H3
• chave InChI: CGAZNAYDEAJZHQ-UHFFFAOYSA-N

Descrição

Descrição geral

Acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM. Hydrolysis by non-specific esterases traps the indicator in the cytosol. Compared to FURA-2, it is retained longer in the cell. Note: 1 set = 10 x 50 µg.

An acetoxymethyl (AM) derivative of FURA-PE3. with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM (Cat. No. 344905). Hydrolysis by non-specific esterases traps the indicator in the cytosol. Spectral properties in the presence of low calcium concentrations (ex. 364 nm, em. 508 nm) differ from those during high calcium conditions (ex. 335 nm, em. 495 nm). Note: 1 set = 10 x 50 µg.

Ações bioquímicas/fisiológicas

Cell permeable: no

Primary Target
Calcium Probes

Product does not compete with ATP.

Reversible: no

Advertência

Toxicity: Standard Handling (A)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Outras notas

Abe, F., et al. 1995. Br. J. Pharmacol.116, 3000.
Vorndran, C., et al. 1995. Biophys. J.69, 2114.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable