341482

Ferritin, Human Liver

Ferritin, Human Liver, CAS 9007-73-2, is a native, sterile-filtered ferritin that is suitable for use in immunoassays, as an immunogen, and in enzyme/radiolabeling.

• Sinônimo(s): Ferritin, Human Liver
• Número CAS: 9007-73-2
• Número MDL: MFCD00081593
• Código UNSPSC: 12352202
• NACRES: NA.77

Propriedades

• fonte biológica: human
• Nível de qualidade: 100
• descrição: RTECS - LK0500000
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: liquid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: do not freeze
• técnica(s): enzyme immunoassay: suitable
• Impurezas: Antibodies to HIV1, HIV2, Hepatitis B, Hepatitis C, tested negative (by certified tests)
• solubilidade: water: soluble
• adequação: suitable for immunoassay
• nº de adesão de ID de proteína: AAA35832.1
• nº de adesão UniProt: P02792; P02794
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• Informações sobre genes: human ... FTH1(2495) , FTL(2512)

Descrição

Descrição geral

Research area: Cell signaling

Ferritin is a major iron storage protein. It exists in a two functionally and genetically different subunits namely, the acidic, heavy or H-chain and the basic, light or L-chain.[1] Native ferritin from human liver. Sterile-filtered.

Aplicação

Ferritin is suitable for use in immunofluorescence assay,[2] immunoassays, as an immunogen, and in enzyme/radiolabeling.

Ações bioquímicas/fisiológicas

Ferritin is a crucial protein that has multiple functions in iron metabolism and immune regulation. It helps in maintaining the iron balance.[3] H-ferritin is involved in various processes such as regulating immune function, hematopoiesis, hepatocyte apoptosis, and cell differentiation. Additionally, ferritin can act as a proinflammatory cytokine through protein kinase C-zeta (PKC-ζ) and nuclear factor kappa B (NFκB) signaling pathways in certain cells.(1) Ferritin serves as both an immune-suppressor and a signaling molecule, contributing to the regulation of lymphoid and myeloid cell proliferation.[4]

Embalagem

Please refer to vial label for lot-specific concentration.

Advertência

Toxicity: Standard Handling (A)

forma física

In 0.9% NaCl, 0.1% NaN₃, pH 7.0.

Outras notas

Addison, J.M., et al. 1983. FEBS Lett.164, 139.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable