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05-1416

Sigma-Aldrich

Anti-CD45 Antibody, clone IBL-5/25

clone IBL-5/25, from rat

Sinônimo(s):

CD45 associated protein, CD45-associated protein, Lymphocyte phosphatase-associated phosphoprotein, PTPRC-associated protein, protein tyrosine phosphatase, receptor type, C-associated protein, protein tyrosine phosphatase, receptor type, c

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rat

Nível de qualidade

100

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

IBL-5/25, monoclonal

reatividade de espécies

mouse

técnica(s)

flow cytometry: suitable
immunohistochemistry: suitable

Isotipo

IgG

nº de adesão NCBI

NP_002829.2

nº de adesão UniProt

Q14761

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Ptprc(19264)

Categorias relacionadas

Descrição geral

CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.

Especificidade

Reactivity with other species has not been determined.
This antibody reacts with all isoforms of mouse CD45 which is expressed on all haematopoietic cells except erythrocytes.
FUSION PARTNER: SP2/0 myeloma cell line

Imunogênio

Mouse lymph node cells.

Aplicação

Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.
Flow Cytometry Analysis: A previous lot detected CD45, clone IBL-5/25 in mouse peripheral blood lymphocytes

Qualidade

Evaluated by Immunohistochemistry in mouse colon tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.

Descrição-alvo

Approx. 147 kDa

Ligação

Replaces: CBL1326

forma física

Format: Purified
Purified rat monoclonal IgG in phosphate buffered saline containing 10 mM sodium azide.

Armazenamento e estabilidade

Store at 2-8°C for 12 months from date of receipt.

Nota de análise

Control
Mouse colon tissue

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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