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LM1304

Avanti

17:0-14:1 PS

Avanti Research™ - A Croda Brand LM1304, methanol solution

Sinônimo(s):

1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-L-serine (ammonium salt)

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R$ 781,00

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About This Item

Fórmula empírica (Notação de Hill):
C37H73N2O10P
Número CAS:
1036814-91-1
Peso molecular:
736.96
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 781,00

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Formulário

methanol solution

embalagem

pkg of 1 × 1 mL (LM1304-1EA)

fabricante/nome comercial

Avanti Research™ - A Croda Brand LM1304

concentração

~10 μg/mL (Refer to C of A for lot specific concentration. )

aplicação(ões)

lipidomics
metabolomics

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

chave InChI

ZBOCVGFQVSWMHT-BPNWTSRKSA-N

Descrição geral

Phosphatidylserine (PS) is an acidic phospholipid present in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues.[1]

Aplicação

17:0-14:1 PS or 1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-L-serine has been used as an internal standard:
  • for the detection of lipids by tandem mass spectrometry (MS/MS)[2]
  • to determine lipid concentration in human primary myotubes lipid extracts by mass spectrometry (MS) analysis[3]
  • for phospholipid quantification by MS[4]
  • for lipid extraction by methyl tert-butyl ether (MTBE) method[5]
  • for lipid quantification using liquid chromatography (LC)-MS[1]

Ações bioquímicas/fisiológicas

Phosphatidylserine (PS) is associated with the Akt, protein kinase C (PKC) and Raf-1 signaling. It supports neuronal survival, neurite growth and synaptogenesis.[1]

Embalagem

2 mL Amber Glass Sealed Ampule (LM1304-1EA)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup

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Hee-Yong Kim et al.
Progress in lipid research, 56, 1-18 (2014-07-06)
Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the inner leaflet of the plasma membrane in neural tissues. PS is synthesized from phosphatidylcholine or phosphatidylethanolamine by exchanging the base head group with serine, and this reaction is
Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
Laurent Perrin et al.
eLife, 7 (2018-04-17)
Circadian regulation of transcriptional processes has a broad impact on cell metabolism. Here, we compared the diurnal transcriptome of human skeletal muscle conducted on serial muscle biopsies in vivo with profiles of human skeletal myotubes synchronized in vitro. More extensive
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to
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