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890870C

Avanti

16:0 TAP

Avanti Research™ - A Croda Brand 890870C

Sinônimo(s):

1,2-dipalmitoyl-3-trimethylammonium-propane (chloride salt)

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About This Item

Fórmula empírica (Notação de Hill):
C38H76NO4Cl
Número CAS:
139984-36-4
Peso molecular:
646.47
Número MDL:
MFCD22495361
Código UNSPSC:
12352211
NACRES:
NA.25
Preço e disponibilidade não estão disponíveis no momento.

Formulário

liquid

embalagem

pkg of 1 × 2.5 mL (890870C-25mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 890870C

concentração

10 mg/mL (890870C-25mg)

tipo de lipídio

cationic lipids
transfection

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Cl-]

InChI

1S/C38H76NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-37(40)42-35-36(34-39(3,4)5)43-38(41)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h36H,6-35H2,1-5H3;1H/q+1;/p-1

chave InChI

KYARZEFZZOGPGS-UHFFFAOYSA-M

Descrição geral

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is a cationic lipid and a diol based transfection reagent.

Aplicação

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is suitable to prepare lipid monolayer/liposome:
  • to mimic the presence of the cationic charge localized in the membrane for understanding the electrostatic effects in the biological membranes and to study its interaction with zearalenone and selenate ions[1]
  • to study its effect on the L-pro catalyzed reaction[2]
  • to serve as a positive control, to determine the effectiveness of anionic phospholipids for pro-inflammatory responses[3]

Ações bioquímicas/fisiológicas

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) liposomes are known to promote elevated pro-inflammatory responses.[3]

Embalagem

5 mL Clear Glass Sealed Ampule (890870C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system, Liver,Kidney

Classe de risco de água (WGK)

WGK 3

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Certificados de análise (COA)

Lot/Batch Number

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Naomi Benne et al.
Journal of controlled release : official journal of the Controlled Release Society, 291, 135-146 (2018-10-27)
Atherosclerosis is the predominant underlying pathology of many types of cardiovascular disease and is one of the leading causes of death worldwide. It is characterized by the retention of oxidized low-density lipoprotein (ox-LDL) in lipid-rich macrophages (foam cells) in the
Detection of L-Proline-Catalyzed Michael Addition Reaction in Model Biomembrane
Hirose M, et al.
Journal of Chemistry, 2019 (2019)
Barbara Gzyl-Malcher et al.
The Journal of membrane biology, 250(3), 273-284 (2017-04-30)
The impact of zearalenone and selenate ions on the monolayers of 1,2-dipalmitoyl-phosphatidylcholine (DPPC), 1,2-dipalmitoyl-3-trimethylammonium-propane (DPTAP), and the lipid mixtures (phospholipids and galactolipids) extracted from wheat plasmalemma has been studied using Langmuir trough technique and Brewster angle microscopy (BAM). The zearalenone
Chun Liufu et al.
International journal of nanomedicine, 14, 8923-8941 (2019-12-10)
Cancer stem cells (CSCs) are responsible for cancer therapeutic resistance and metastasis. To date, in addition to surgery, chemotherapy, and radiotherapy, gene delivery has emerged as a potential therapeutic modality for ovarian cancer. Efficient and safe targeted gene delivery is
Bao Zhu et al.
Chemosphere, 247, 125876-125876 (2020-01-25)
Aluminium oxide nanoparticles (Al2O3 NPs) potentially cause health hazards after their release into the environment. The crystalline phase of Al2O3 NPs determines their surface structure and the number of functional groups. The adsorption of natural organic matter (NOM) or biomolecules
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