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810110P

Avanti

12-NBD Stearate

Avanti Research™ - A Croda Brand 810110P, powder

Sinônimo(s):

12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazo)aminostearic acid

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1 MG
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About This Item

Fórmula empírica (Notação de Hill):
C25H40N4O5
Número CAS:
117056-67-4
Peso molecular:
476.61
Número MDL:
MFCD00467278
Código UNSPSC:
12352211
NACRES:
NA.25

R$ 2.293,00

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Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 1 mg (810110P-1mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 810110P

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCCCCCCCCCC(=O)O)CCCCCC)C

InChI

1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)

chave InChI

SAAVELCIPHKGJE-UHFFFAOYSA-N

Descrição geral

12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe[1] and is a long-chain fatty acid (LCFA) derivative.[2]

Aplicação

12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films[3] and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay.[4] It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).[5]

Ações bioquímicas/fisiológicas

12-NBD Stearate incorporated in lipid droplets[1] and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins.[6] The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport.[1] The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake[7] and inhibited by filipin III.[2]

Embalagem

5 mL Amber Glass Screw Cap Vial (810110P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

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Certificados de análise (COA)

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Lu Bai et al.
ACS infectious diseases, 6(4), 637-648 (2020-02-14)
Assembly of the bacterial cell wall requires not only the biosynthesis of cell wall components but also the transport of these metabolites to the cell exterior for assembly into polymers and membranes required for bacterial viability and virulence. LprG is
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
Testing, 7(12) (2012)
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
PLoS ONE, 7(12) (2012)
Tracking of drug release and material fate for naturally derived omega-3 fatty acid biomaterials
Faucher KM, et al.
Annals of Biomedical Engineering, 44(3), 782-792 (2016)
Gregory Carbonetti et al.
Scientific reports, 9(1), 18944-18944 (2019-12-14)
Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by upregulation of lipid metabolism-related genes including fatty acid binding protein 5 (FABP5), fatty acid synthase (FASN), and monoacylglycerol lipase (MAGL). FASN and MAGL are enzymes that generate
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