700039P

24(S),25-epoxycholesterol

Avanti Research^™ - A Croda Brand

• Sinônimo(s): (24S,25)-Epoxycholesterol, (3β,24S)-24,25-Epoxycholest-5-en-3-ol
• Fórmula empírica (Notação de Hill): C₂₇H₄₄O₂
• Número CAS: 77058-74-3
• Peso molecular: 400.64
• Número MDL: MFCD03695562
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Formulário: powder
• embalagem: pkg of 1 × 1 mg (700039P-1mg); pkg of 1 × 5 mg (700039P-5mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O1[C@H](C1(C)C)CC[C@H]([C@@H]2[C@@]3([C@H]([C@H]4[C@@H]([C@]5(CC[C@@H](CC5=CC4)O)C)CC3)CC2)C)C
• InChI: 1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1
• chave InChI: OSENKJZWYQXHBN-XVYZBDJZSA-N

Descrição

Descrição geral

24(S),25-epoxycholesterol is an oxysterol, which is produced by fibroblasts, macrophages and brain cells.

24(S),25-epoxycholesterol is a cholesterol-derived oxysterol, which is produced by fibroblasts, macrophages, and the brain cells. 24(S),25-epoxycholesterol is synthesized de novo in the mevalonate pathway.

Aplicação

24(S),25-epoxycholesterol has been used as an oxysterol/internalstandard to study the effects of AY9944-induced changes in neurospheres.

Ações bioquímicas/fisiológicas

Exogenous addition of 24(S),25-epoxycholesterol lowers 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase activity, represses sterol regulatory element-binding protein (SREBP) processing, and induces liver × receptor (LXR) -gene targets in vitro.

Embalagem

5 mL Amber Glass Screw Cap Vial (700039P-1mg)

5 mL Amber Glass Screw Cap Vial (700039P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids