QBD10512

Azido-dPEG^®₈-acid

• Sinônimo(s): Polyethylene glycol
• Fórmula empírica (Notação de Hill): C₁₉H₃₇N₃O₁₀
• Número CAS: 1214319-92-2
• Peso molecular: 467.51
• Número MDL: MFCD21363300
• Código UNSPSC: 12352106
• ID de substância PubChem: 329823934
• NACRES: NA.22

Propriedades

• Ensaio: >90%
• forma: solid or viscous liquid
• adequação da reação: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• grupo funcional: azide; carboxylic acid
• arquitetura do polímero: shape: linear; functionality: heterobifunctional
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Descrição

Características e benefícios

The azido-dPEG^®₈ contains an azide function on one end of a single molecular weight dPEG^® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Informações legais

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable