(±)-α-Methoxyphenylacetic acid, also known as MOPA is commonly used as a resolving agent and building block in various organic synthesis.
Aplicação
(±)-α-Methoxyphenylacetic acid can be used as a reactant to synthesize:
N
-(Cyclohexylmethyl)-2-methoxy-2-phenylethylamine by reacting with cyclohexylmethylamine in the presence of EDCI/HOBt/Et3N.
4-(methoxyphenylmethyl)-2-methylpyridine by reacting with 2-methyl-4-pyridinecarbonitrile via decarboxylative arylation reaction in the presence of a photocatalyst.
The Journal of organic chemistry, 82(13), 6748-6763 (2017-06-13)
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