55088
8-Hydroxy-2-quinolinecarboxylic acid
≥98.0% (HPLC)
Sinônimo(s):
8-Hydroxyquinaldic acid
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About This Item
Fórmula empírica (Notação de Hill):
C10H7NO3
Número CAS:
Peso molecular:
189.17
Beilstein:
146082
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
Preço e disponibilidade não estão disponíveis no momento.
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Ensaio
≥98.0% (HPLC)
Formulário
solid
grupo funcional
carboxylic acid
cadeia de caracteres SMILES
OC(=O)c1ccc2cccc(O)c2n1
InChI
1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)
chave InChI
UHBIKXOBLZWFKM-UHFFFAOYSA-N
Categorias relacionadas
Descrição geral
8-Hydroxy-2-quinolinecarboxylic acid (8HQC) is a tridentate chelating agent.[1] It reacts with 2-aminophenol to form a benzoxazole derivative, which can undergo fluorescence quenching in water, making it a viable candidate for developing a probe for detecting water in aprotic organic solvents.[2] The analysis of mid-IR and Raman spectra of 8HQC shows the presence of seven tautomers.[3]
Aplicação
8-Hydroxy-2-quinolinecarboxylic acid may be used in the preparation of bis (8-hydroxyquinoline-2-carboxylato-Κ3N,O,O′) cobalt (II) trihydrate.[1]
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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Molecules (Basel, Switzerland), 25(7) (2020-04-09)
8-Hydroxyquinaldic acid, the end-metabolite of tryptophan, is well-known metal chelator; however, its role in humans, especially in cancer promotion and progression, has not been fully revealed. Importantly, 8-hydroxyquinaldic acid is the analog of kynurenic acid with evidenced antiproliferative activity towards
Bis (8-hydroxyquinoline-2-carboxylato-?3N,O,O') cobalt (II) trihydrate.
Okabe N and Muranishi Y.
Acta Crystallographica Section E, Structure Reports Online, 58(7), m352-m353 (2002)
Determination of water content in aprotic organic solvents using 8-hydroxyquinoline based fluorescent probe.
Kim JS, et al.
Bull. Korean Chem. Soc., 27(12), 2058-2058 (2006)
A combined experimental and theoretical study on 8-hydroxy-2-quinolinecarboxylic acid.
Badoglu S and Yurdakul S.
Optics and Spectroscopy, 116(2), 196-206 (2014)
Francesco Bellia et al.
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Metal dysregulation, oxidative stress, protein modification, and aggregation are factors strictly interrelated and associated with neurodegenerative pathologies. As such, all of these aspects represent valid targets to counteract neurodegeneration and, therefore, the development of metal-binding compounds with other properties to
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