394238

Pyrrolidine

≥99.5%, purified by redistillation

• Sinônimo(s): Tetrahydropyrrole, Tetramethyleneimine
• Fórmula empírica (Notação de Hill): C₄H₉N
• Número CAS: 123-75-1
• Peso molecular: 71.12
• Beilstein: 102395
• Número CE: 204-648-7
• Número MDL: MFCD00005249
• Código UNSPSC: 12352100
• ID de substância PubChem: 24864581
• NACRES: NA.22

Propriedades

• densidade de vapor: 2.45 (vs air)
• pressão de vapor: 128 mmHg ( 39 °C); 49 mmHg ( 20 °C)
• Ensaio: ≥99.5%
• Formulário: liquid
• temperatura de autoignição: 653 °F
• purificado por: redistillation
• Lim. expl.: 10.6 %
• índice de refração: n20/D 1.443 (lit.)
• solubilidade: water: miscible
• densidade: 0.852 g/mL at 25 °C (lit.)
• cadeia de caracteres SMILES: C1CCNC1
• InChI: 1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2
• chave InChI: RWRDLPDLKQPQOW-UHFFFAOYSA-N

Descrição

Descrição geral

Pyrrolidine is a five membered cyclic amine. It is a nitrogen heterocycle that forms the nucleus of various bioactive molecules. It can be synthesized by reacting 1,4-diaminobutanes with acids. It behaves as a strong base in employed in certain homogeneous nonaqueous reactions.[1] Its crystalline structure has been investigated.[2] Its reaction on the Ge(100)-2×1 surface and Si(100)-2×1 surface has been investigated.[3] Pyrrolidine has been found to be one of the component of volatile amine fraction in the brewing process.[4] A study on the kinetics of pyrrolidinolysis of phthalimide (PTH) shows second- and third-order terms in the rate law.[5] Biodegradation of pyrrolidine by Mycobacterium strains has been studied.[6]

Aplicação

Pyrrolidine may be used in the following studies:

• Synthesis of pyrrolidine derivatives of pyrimidine.[7]
• As a catalyst in the selective monoallylation of allylic alcohols.[8]
• To capture carbondioxide in a bubble column reactor using pyrrolidine aqueous solutions by gas–liquid absorption.[9]

Informações de segurança

• Pictogramas: GHS02,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H225,H302 + H332,H314
• Declarações de precaução: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 37.4 °F - closed cup
• Ponto de fulgor (°C): 3 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter