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Merck

PDE4C

phosphodiesterase 4C, cAMP-specific

Sinônimos:
DPDE1
Espécies:
Human PDE4C (5143), Mouse Pde4c (110385), Rat Pde4c (290646), dog PDE4C (609938), cow PDE4C (524624), domestic cat PDE4C (101086123), naked mole-rat Pde4c (101703048), sheep PDE4C (101111282)
ID UniProtKB:
Q08493, B3KTC4, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6
ID do gene:
  • Human(5143) Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(110385) phosphodiesterase 4C, cAMP specific
  • Rat(290646) phosphodiesterase 4C, cAMP-specific
  • dog(609938) phosphodiesterase 4C, cAMP-specific
  • cow(524624) phosphodiesterase 4C, cAMP-specific
  • domestic cat(101086123) phosphodiesterase 4C, cAMP-specific
  • naked mole-rat(101703048) phosphodiesterase 4C, cAMP-specific
  • sheep(101111282) phosphodiesterase 4C, cAMP-specific

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Small Molecule - Antagonist

Número do produto
Descrição
Espécies
A1755
Aminophylline, ≥98%, powder,
Espécies
human
PHL82668
Theophylline, phyproof® Reference Substance,
Espécies
human
PHR1023
Theophylline, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
T0800000
Theophylline, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
BP327
Theophylline, British Pharmacopoeia (BP) Reference Standard,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
HPA048975
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
SAB1404183
Monoclonal Anti-PDE4C, (N-terminal) antibody produced in mouse, clone 4E5, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
western blot
SAB1400197
Monoclonal Anti-PDE4C antibody produced in mouse, clone 6A10, ascites fluid,
Reatividade de espécies
human
Aplicação
ELISA
western blot
HPA054218
Anti-PDE4C antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
SML1099
Roflumilast, ≥98% (HPLC),
Espécies
human
SML0517
Amlexanox, ≥98% (HPLC),
Espécies
human
I0157
Ibudilast, ≥99% (HPLC), solid,
Espécies
human
D0633
7-(2,3-Dihydroxypropyl)theophylline, ,
Espécies
human
D2800000
Diprophylline, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

Proteins

Número do produto
Descrição
Espécies
SRP0265
PDE4C Active from mouse, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Espécies
mouse
SRP0266
PDE4C1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU043571
MISSION® esiRNA, targeting mouse Pde4c,
Espécies
mouse
EHU060201
MISSION® esiRNA, targeting human PDE4C,
Espécies
human