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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Sinônimos:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Espécies:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...Mais
ID UniProtKB:
P28222, Q4VAY7
ID do gene:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
S1198
Sumatriptan succinate, ≥98% (HPLC), solid,
Espécies
human
SML0248
Zolmitriptan, ≥98% (HPLC),
Espécies
human
SML1291
Frovatriptan succinate monohydrate, ≥97% (HPLC),
Espécies
human
N1415
Naratriptan hydrochloride, ≥98% (HPLC),
Espécies
human
SML0247
Rizatriptan benzoate salt, ≥98% (HPLC),
Espécies
human

Small Molecule - Allosteric Modulator

Número do produto
Descrição
Espécies
D9190
DCEBIO, ≥98% (HPLC), solid,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
G5793
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
Espécies
human
M149
Methiothepin mesylate salt, ≥98% (HPLC), solid,
Espécies
human
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Espécies
human
M3668
Metergoline, ,
Espécies
human, rat
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Espécies
human, rat

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
MABN1539
Anti-Serotonin Receptor 1B Antibody, clone 1C2.1, clone 1C2.1, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
SAB4501471
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
western blot
SAB2500924
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
canine, human, mouse, rat
Aplicação
ELISA
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Espécies
human
Z101
Zimelidine dihydrochloride, solid,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
R0875
Reserpine, ,
Espécies
human
I119
Indatraline hydrochloride, solid,
Espécies
human
M8046
Mifepristone, ≥98%,
Espécies
human, mouse, rat
51330
Harmaline, ≥95%,
Espécies
human, rat

Small Molecule - Ligand

Número do produto
Descrição
Espécies
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Espécies
human

Small Molecule - Metabolite

Número do produto
Descrição
Espécies
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Espécies
human

Small Molecule - Precursor

Número do produto
Descrição
Espécies
H9772
5-Hydroxy-L-tryptophan, powder,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
Espécies
mouse