CASP3
caspase 3, apoptosis-related cysteine peptidase
Sinônimos:
CPP32, CPP32B, SCA-1
Espécies:
Human CASP3 (836), Mouse Casp3 (12367), Rat Casp3 (25402), dog CASP3 (403567), chicken CASP3 (395476), naked mole-rat Casp3 (101712867), domestic guinea pig Casp3 (100718309), cow CASP3 (408016), Domestic Rabbit CASP3 (100008840), sheep CASP3 (443031) ...Mais
ID UniProtKB:
ID do gene:
- Human(836) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(12367) caspase 3
- Rat(25402) caspase 3
- dog(403567) caspase 3, apoptosis-related cysteine peptidase
- chicken(395476) caspase 3, apoptosis-related cysteine peptidase
- naked mole-rat(101712867) caspase 3, apoptosis-related cysteine peptidase
- domestic guinea pig(100718309) caspase 3, apoptosis-related cysteine peptidase
- cow(408016) caspase 3, apoptosis-related cysteine peptidase
- Domestic Rabbit(100008840) caspase 3, apoptosis-related cysteine peptidase
- sheep(443031) caspase 3, apoptosis-related cysteine peptidase
- domestic cat(493932) caspase 3, apoptosis-related cysteine peptidase
- Horse(100034083) caspase 3, apoptosis-related cysteine peptidase
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Activity Assay
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anticorpo anticaspase 3, forma ativa (clivada), Chemicon®, from rabbit,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
western blot
Anti-Caspase 3 Antibody, from rabbit, purified by affinity chromatography,
Reatividade de espécies
canine, feline, hamster, human, mouse, nonhuman primates, rat
Aplicação
immunocytochemistry
western blot
western blot
Anti-Caspase-3 Antibody, clone 3J16 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
bovine, human, mouse, rat
Aplicação
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Caspase 3 Antibody, Upstate®, from rabbit,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Kits
Número do produto
Descrição
Espécies
Kit de ensaio de atividade colorimétrica da caspase 3, DEVD, Caspase-3 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the sequence DEVD.,
Espécies
human
CaspaTag Caspase 3,7 In Situ Assay Kit, Fluorescein, The In Situ Caspase Detection Kit for Flow Cytometry use a novel approach to detect active caspases. The methodology is based on Fluorochrome Inhibitors of Caspases (FLICA).,
Espécies
human
Caspase 3 Colorimetric Activity Assay Kit, DEVD, Caspase-3 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the sequence DEVD.,
Espécies
human
CaspaTag Caspase 3,7 In Situ Assay Kit, Fluorescein, The CaspaTag Caspase-3/7 In Situ Assay Kit, Fluorescein for Flow Cytometry is a fluorescent-based assay for detection of active caspase-3 or caspase-7 in cells undergoing apoptosis.,
Espécies
human
Proteins
Número do produto
Descrição
Espécies
Caspase 3 human, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous glycerol solution, ≥1.0 units/mg protein,
Espécies
human
esiRNA
Número do produto
Descrição
Espécies