Accéder au contenu
Merck
Toutes les photos(1)

Documents

RAB0448

Sigma-Aldrich

Cell-Based ELISA for detecting phospho-STAT4 (pTyr693) in cultured cell lines

96 assays

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.84

Utilisation

96 assays

Espèces réactives

mouse, human

Technique(s)

ELISA: suitable
capture ELISA: suitable

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... STAT4(6775)
mouse ... STAT4(20849)

Description générale

The Cell-Based Stat4 (pTyr693) ELISA kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cells. It can be used for measuring the relative amount of Stat4 (pTyr693) phosphorylation and screening the effects of various treatments, inhibitors (such as siRNA or chemicals), or activators in cultured human and mouse cell lines.

Immunogène

Stat4 (pTyr693) synthetic phosphopeptide

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS
  • RABBLOCK5x Blocking Solution (Item F)FDS
  • RABFIX1Fixing Solution (Item D)FDS
  • RABHRP1HRP-conjugated Anti-Rabbit IgG Concentrate (Item I1)FDS
  • RABHRP2HRP-conjugated Anti-Mouse IgG Concentrate (Item I2)FDS
  • RABPLATE1Uncoated MicroplateFDS
  • RABQUENCHQuenching Solution for Cell-based ELISA Assay (Item E)FDS
  • RABSTOP1Stop SolutionFDS
  • RABTMB1TMB Substrate Reagent (Item J)FDS
  • RABWASH120X Wash Buffer Concentrate AFDS
  • RABWASH220X Wash Buffer Concentrate BFDS
Afficher tout (10)

Pictogrammes

Health hazardCorrosionExclamation mark
GHS08,GHS05,GHS07

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Hua-Chen Chang et al.
The Journal of biological chemistry, 278(34), 32471-32477 (2003-06-14)
STAT4 (signal transducer and activator of transcription-4) mediates biological effects in response to interleukin-12 (IL-12). STAT4 has multiple domains that have distinct functions in signaling and gene activation. To characterize the role of the STAT4 N-terminal domain in mediating STAT4
K Yamamoto et al.
Molecular and cellular biology, 14(7), 4342-4349 (1994-07-01)
Interferon regulation of gene expression is dependent on the tyrosine phosphorylation and activation of the DNA-binding activity of two related proteins of 91 kDa (STAT1) and/or 113 kDa (STAT2). Recent studies have suggested that these proteins are substrates of Janus
C M Bacon et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(16), 7307-7311 (1995-08-01)
Interleukin 12 (IL-12) is an important immunoregulatory cytokine whose receptor is a member of the hematopoietin receptor superfamily. We have recently demonstrated that stimulation of human T and natural killer cells with IL-12 induces tyrosine phosphorylation of the Janus family

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique