Accéder au contenu
Merck
Toutes les photos(4)

Principaux documents

FD70S

Sigma-Aldrich

Isothiocyanate-dextrane marqué à la fluorescence

average mol wt 60,000-76,000

Synonyme(s) :

FITC-dextrane

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Sélectionner une taille de conditionnement

100 MG
134,00 €
250 MG
276,00 €
1 G
838,00 €
5 G
2 640,00 €

134,00 €


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
100 MG
134,00 €
250 MG
276,00 €
1 G
838,00 €
5 G
2 640,00 €

About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

134,00 €


Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.

Devis pour commande en gros

Source biologique

bacterial (Leuconostoc mesenteroides)

Conjugué

FITC conjugate

Forme

powder

Poids mol.

average mol wt 60,000-76,000

Ampleur du marquage

0.003-0.020 mol FITC per mol glucose

Couleur

yellow to yellow-orange

Solubilité

H2O: 25 mg/mL, clear to slightly hazy, yellow-orange

Température de stockage

2-8°C

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Dextrane marqué à l′isothiocyanate de fluorescéine pour utilisation potentielle dans les études de perfusion chez l′animal.
FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.[1] Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability.[2] FITC-dextran 70 kDa (FD-70) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. FD-70 may be used in microvascular and cell monolayer permeability studies.[3]

Liaison

Similar to FD-70, but produced by Sigma.

Autres remarques

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Maira Carrillo et al.
Medicine, 97(39), e12392-e12392 (2018-10-04)
Imaging of placental tissues is a difficult task, because of specific for this organ complex multicellular and 3D tissue structure. The tissue clearing systems (X-CLARITY) system is a valuable tool for the examining the expression of molecular pathways in whole
Gabriela Hurtado-Alvarado et al.
PloS one, 11(11), e0167236-e0167236 (2016-11-29)
Chronic sleep restriction induces blood-brain barrier disruption and increases pro-inflammatory mediators in rodents. Those inflammatory mediators may modulate the blood-brain barrier and constitute a link between sleep loss and blood-brain barrier physiology. We propose that adenosine action on its A2A
Haruo Aramoto et al.
American journal of physiology. Heart and circulatory physiology, 287(4), H1590-H1598 (2004-05-25)
Vascular endothelial growth factor (VEGF) induces mild vasodilation and strong increases in microvascular permeability. Using intravital microscopy and digital integrated optical intensity image analysis, we tested, in the hamster cheek pouch microcirculation, the hypothesis that differential signaling pathways in arterioles
Michael J Shirey et al.
Journal of neurophysiology, 114(1), 309-322 (2015-05-15)
Changes in brain temperature can alter electrical properties of neurons and cause changes in behavior. However, it is not well understood how behaviors, like locomotion, or experimental manipulations, like anesthesia, alter brain temperature. We implanted thermocouples in sensorimotor cortex of
Ziba Roveimiab et al.
American journal of physiology. Cell physiology, 319(1), C75-C92 (2020-04-30)
Cell migration is central to development, wound healing, tissue regeneration, and immunity. Despite extensive knowledge of muscle regeneration, myoblast migration during regeneration is not well understood. C2C12 mouse myoblast migration and morphology were investigated using a triple-docking polydimethylsiloxane-based microfluidic device

Contenu apparenté

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Questions

1–2 of 2 Questions  
  1. Is this dextran lysine-fixable?

    1 answer
    1. This product is not considered lysine-fixable. The material would have to be chemically treated in order to be suitable. Typically, dextrans used to prepare lysine-fixable products are anionic (see product 90718). Should it be of interest, product B9139 is a Biotin-dextran, lysine-fixable product option. See the link below to review this product page:
      https://www.sigmaaldrich.com/product/sigma/b9139

      Helpful?

  2. How long would a diluted stock (i.e. 5 mg/mL) be stable for at 4C?

    1 answer
    1. The long term solution stability of this product has not been determined. Solutions should be protected from light. Per literature references, FITC-Dextran is stable in vivo for more than 24 hours. Please see the link below for additional information.
      https://www.sigmaaldrich.com/technical-documents/technical-article/cell-culture-and-cell-culture-analysis/cell-based-assays/fluorescein-isothiocyanate-dextran

      Helpful?

Reviews

No rating value

Active Filters

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique