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30549

Sigma-Aldrich

Kollicoat® IR

Synonyme(s) :

Macrogol-poly(vinyl alcohol) graft-copolymer, Polyvinyl alcohol-polyethylene glycol graft-copolymer

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About This Item

Numéro CAS:
96734-39-3
Code UNSPSC :
12162002
Nomenclature NACRES :
NA.25

Impuretés

ethylene glycol, complies (meets the requirements of Macrogol Polyvinylalcohol Grafted Copolymer Ph Eur Ed. 7)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤100 ppm vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals

Résidus de calcination

≤2%

Perte

≤5% loss on drying

pH

5.0-8.0 (20% in H2O)

Viscosité

50-250 mPa.s, 20 %(23 °C, Brookfield RVT) (SP.2, 100RPM)

Indice d'ester

10‑70 mg KOH/g

Application

Kollicoat IR is used in the pharmaceutical industry as a binder, pellets, and particulate matter. This research grade product is intended for use in R&D and development only.

Informations légales

Kollicoat is a registered trademark of BASF SE

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Susanne Muschert et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(1), 130-137 (2009-01-17)
The aim of this study was to better understand the underlying drug release mechanisms from aqueous ethylcellulose-coated pellets containing different types of drugs and starter cores. Theophylline, paracetamol, metoprolol succinate, diltiazem HCl and metoprolol tartrate were used as model drugs
Kyung Jin Son et al.
ACS applied materials & interfaces, 3(2), 573-581 (2011-02-05)
In this study, we describe the use of organized mesoporous titanium oxide (TiO(2)) films as three-dimensional templates for protein microarrays with enhanced protein loading capacity and detection sensitivity. Multilayered mesoporous TiO(2) films with high porosity and good connectivity were synthesized
Sandra Guns et al.
Pharmaceutical research, 28(3), 673-682 (2010-11-26)
To investigate the effect of the manufacturing method (spray-drying or hot-melt extrusion) on the kinetic miscibility of miconazole and the graft copolymer poly(ethyleneglycol-g-vinylalcohol). The effect of heat pre-treatment of solutions used for spray-drying and the use of spray-dried copolymer as
Pan Liu et al.
Journal of pharmaceutical sciences, 101(8), 2811-2820 (2012-05-23)
The objective of this study was to investigate the drug release mechanism and in vivo performance of Tanshinone IIA sustained-release pellets, coated with blends of polyvinyl acetate (PVAc) and poly(vinyl alcohol)-poly(ethylene glycol) (PVA-PEG) graft copolymer. A formulation screening study showed

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