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02071

Sigma-Aldrich

Catalase from Corynebacterium glutamicum

solution, deep brown, ≥500000 U/mL

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About This Item

Numéro CAS:
Numéro de classification (Commission des enzymes):
Numéro MDL:
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.54

Source biologique

bacterial (Corynebacterium glutamicum)

Forme

solution

Concentration

≥500000 U/mL

Couleur

deep brown

Conditions d'expédition

wet ice

Température de stockage

2-8°C

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

Clé InChI

NUVBSKCKDOMJSU-UHFFFAOYSA-N

Description générale

Catalase is ubiquitously found in animals, plants, fungi, and humans. It is made up of looped polypeptide chains that are arranged as tetramers or dimers and a core, that contains iron or manganese ions. Catalase can be differentiated into two types such as heme-containing (type I), which possesses an iron-porphyrin cofactor and a non-heme-containing (type II), which possesses a dinuclear manganese active site.

Application

Catalase from Corynebacterium glutamicum has been used to identify and characterize purified bacterial peptide (PPBP) produced from Bacillus thuringiensis. It has also been used to study its inhibition by nitric oxide.

Actions biochimiques/physiologiques

Catalase is an antioxidant enzyme that plays a role in alleviating oxidative stress by the removal of hydrogen peroxide to produce oxygen and water. Lower levels of catalase lead to several age-related disorders including hypertension, anemia, vitiligo, Parkinson′s disease, Alzheimer′s disease, schizophrenia, bipolar disorders, diabetes mellitus, and cancer.

Définition de l'unité

1 U corresponds to the amount of enzyme which decomposes 1 μmol H2O2 per minute at pH 7.0 and 25°C

Forme physique

contains ~30% glycerol, 10% ethanol

Pictogrammes

Flame

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Flam. Liq. 3

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

105.8 °F - closed cup

Point d'éclair (°C)

41 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Nitin Kumar et al.
Science advances, 4(10), eaat7779-eaat7779 (2018-10-20)
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Zh P Kopteva et al.
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(1), 41-47 (2013-03-23)
Lipolytic and catalase activity of Pseudomonas pseudoalcaligenes 109, Rhodococcus erythropolis 102, Bacillus subtilis 138 and their association with different growth models: biofilm and plankton ones. It is shown that under biofilm conditions the fermentative activity of bacteria under study was
L V Barabash
Klinicheskaia laboratornaia diagnostika, (12)(12), 14-17 (2013-03-14)
The technique of cosinor-analysis was applied to study the oncological dynamics of hormonal and lipid status, activity of peroxide oxidation of lipids in 580 healthy males and females residing in the Western Siberia. The clear circannual rhythm of gluco-corticoid function
Angela Sacchi et al.
Environmental pollution (Barking, Essex : 1987), 177, 82-89 (2013-03-12)
Coastal lagoons are constantly subjected to releases of chemical pollutants, and so organisms may be exposed to such toxicants. This study investigated through a multivariate approach the physiological status of bivalve Ruditapes philippinarum, farmed in Sacca di Goro lagoon. Biomarkers
Danielle de Lima Ávila et al.
Archives of medical research, 44(3), 194-202 (2013-03-26)
It is believed that oxidative stress plays a role in the pathogenesis of diabetes mellitus. Several strategies have been developed with the objective of minimizing diabetic complications. Among these, inhibitors of dipeptidyl peptidase-IV (DPP-IV), which act by blocking degradation of

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