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R7649

Sigma-Aldrich

(−)-Riboflavine

meets USP testing specifications

Synonyme(s) :

Lactoflavin, Vitamin B2, Vitamin G

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25 G
79,70 €
100 G
254,00 €
500 G
982,00 €
1 KG
1 840,00 €

79,70 €

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Toutes les photos(6)

Sélectionner une taille de conditionnement

Changer de vue
25 G
79,70 €
100 G
254,00 €
500 G
982,00 €
1 KG
1 840,00 €

About This Item

Formule empirique (notation de Hill) :
C17H20N4O6
Numéro CAS:
83-88-5
Poids moléculaire :
376.36
Beilstein:
97825
Numéro CE :
201-507-1
Numéro MDL:
MFCD00005022
Code UNSPSC :
12352205
eCl@ss :
34058005
ID de substance PubChem :
24899397
Nomenclature NACRES :
NA.21

79,70 €

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Devis pour commande en gros

Agence

USP/NF
meets USP testing specifications

Niveau de qualité

200

Essai

98.0-102.0% dry basis

Forme

powder

Couleur

dark yellow

Pf

290 °C (dec.) (lit.)

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

Clé InChI

AUNGANRZJHBGPY-SCRDCRAPSA-N

Catégories apparentées

Description générale

Riboflavin is an essential vitamin soluble in water. Milk and eggs are found to be its major sources. Riboflavin is usually bound to enzymes in all tissues. During riboflavin localization in plasma, it is bound to albumin and specific immunoglobulins.[1]

Application

(-)-Riboflavin has been used to study its antimicrobial effect in vitro,[2] through ultraviolet light A (UVA) activation.[3][4]It has also been used collagen coated surface of the polyethylene membrane for cross-linking astrocytes.[5]

Actions biochimiques/physiologiques

Riboflavin serves as a precursor for the active enzyme cofactors riboflavin 5′-monophosphate (also called flavin mononucleotide or FMN) and flavin adenine dinucleotide (FAD).[1] Riboflavin deficiency in the diet results in a well-defined syndrome known as ariboflavinosis,[6] Riboflavin exhibits protective effects against tumor development and cardiovascular disease. Its deficiency often affects metabolism involving redox reactions. Riboflavin is found essential for iron absorption, gastrointestinal development, neurogenesis, corneal vascularization and corneal opacity.[1]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
WXBF4481V
WXBF3135V
WXBF2908V
WXBF3750V
WXBF2181V

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Consulter la Bibliothèque de documents

Evaluation of antibacterial efficacy of photo-activated riboflavin using ultraviolet light (UVA)
Makdoumi K, et al.
Graefe'S Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie, 248(2), 207-212 (2010)
Graciely Gomes Correa et al.
Data in brief, 31, 105736-105736 (2020-06-09)
Modular and tuneable genetic tools for Metabolic Engineering fuels the development of chassis for the efficient production of biocompounds at industrial scale. We have constructed an autoinduction device for gene expression in Bacillus subtilis based on the LuxR/I quorum sensing
Mechanical stretching elevates peptidyl arginine deiminase 2 expression in astrocytes
Algeciras ME, et al.
Current Eye Research, 33(11-12), 994-1001 (2008)
Photochemical eradication of methicillin-resistant Staphylococcus aureus by blue light activation of riboflavin
Makdoumi K, et al.
Acta Ophthalmologica, 95(5), 498-502 (2017)
The efficiency of cross-linking methods in eradication of bacteria is influenced by the riboflavin concentration and the irradiation time of ultraviolet light
Backman A, et al.
Acta Ophthalmologica, 92(7), 656-661 (2014)
Afficher tous les articles scientifiques apparentés

Articles

Riboflavin in Cell Culture

Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.

Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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