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R7774

Sigma-Aldrich

Riboflavin 5′-phosphate sodium salt hydrate

meets USP testing specifications

Synonyme(s) :

Flavin Mononucleotide

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10 G
83,40 €
25 G
172,00 €
100 G
482,00 €

About This Item

Formule empirique (notation de Hill) :
C17H20N4NaO9P · xH2O
Poids moléculaire :
478.33 (anhydrous basis)
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352205
eCl@ss :
34058005
ID de substance PubChem :
Nomenclature NACRES :
NA.21

83,40 €


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Devis pour commande en gros

Agence

USP/NF
meets USP testing specifications

Niveau de qualité

Essai

73.0-79.0% dry basis (BASED ON % RIBOFLAVIN)

Forme

powder

Application(s)

pharmaceutical (small molecule)

Température de stockage

−20°C

Chaîne SMILES 

O.[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C

InChI

1S/C17H21N4O9P.Na.H2O/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);;1H2/q;+1;/p-1/t11-,12+,14-;;/m0../s1

Clé InChI

BHRVCJBIICJWTH-APQIITSESA-M

Description générale

Riboflavin 5′-phosphate (flavin mononucleotide (FMN)) is a vitamin B12 derivative, containing isoalloxazine ring system.[1]

Application

Riboflavin 5′-phosphate sodium salt hydrate has been used:
  • as a photosensitizing agent to assess in vitro efficacy of photodynamic therapy (PDT) on fungi[2]
  • to evaluate its in vivo delivery in rat corneas[3]
  • as a component in Vitamin and growth factor stock mix[4]

Actions biochimiques/physiologiques

Riboflavin 5′-phosphate (flavin mononucleotide (FMN)) acts as a coenzyme in intermediary metabolism. Phosphorylation of vitamin B12 by flavokinase yields FMN.[1]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Cell isolation and culture
WormBook: The Online Review of C. elegans Biology (2005)
Riboflavin (vitamin B2)
Handbook of vitamins, 255-273 (2013)
Heather Durkee et al.
Lasers in medical science, 35(4), 861-866 (2019-12-25)
To evaluate the in vitro efficacy of rose bengal and riboflavin photodynamic antimicrobial therapy for inhibition the growth of four Pseudomonas aeruginosa (P. aeruginosa) isolates. Four different clinical P. aeruginosa isolates were collected from patients with confirmed keratitis. Each strain
Zhi Li et al.
Biochemical and biophysical research communications, 467(3), 503-508 (2015-10-11)
Desulfotomaculum reducens MI-1 is a Firmicute strain capable of reducing a variety of heavy metal ions and has a great potential in heavy metal bioremediation. We recently identified Dred_2421 as a potential iron reductase through proteomic study of D. reducens. The
Johanna Mock et al.
Journal of bacteriology, 196(18), 3303-3314 (2014-07-09)
Moorella thermoacetica can grow with H₂ and CO₂, forming acetic acid from 2 CO₂ via the Wood-Ljungdahl pathway. All enzymes involved in this pathway have been characterized to date, except for methylenetetrahydrofolate reductase (MetF). We report here that the M.

Articles

Riboflavin's impact on cell culture systems for manufacturing proteins and monoclonal antibodies discussed.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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