BP592

Ribavirin-Unreinheit Standard

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): Ribavirin, 1-β-D-Ribofuranosyl-1,2,4-triazol-3-carboxamid
• Empirische Formel (Hill-System): C₈H₁₂N₄O₅
• CAS-Nummer: 36791-04-5
• Molekulargewicht: 244.20
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00058564

Eigenschaften

• grade: pharmaceutical primary standard
• agency: BP
• API family: ribavirin
• form: solid
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• application(s): pharmaceutical; pharmaceutical small molecule
• format: mixture
• storage temp.: 2-8°C
• SMILES string: NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
• InChI: 1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
• InChI key: IWUCXVSUMQZMFG-AFCXAGJDSA-N
• Gene Information: human ... IMPDH1(3614)

Beschreibung

General description

Analog den Imidazol-Nukleotid-Zwischenprodukten in der Purin-Nukleotid-Biosynthese.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ribavirin impurity standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Ribavirin Powder for Nebuliser Solution

Biochem/physiol Actions

Virostatikum, das gegen eine Vielzahl von humanen Virusinfektionen verwendet wird, insbesondere chronischer Hepatitis C, HIV und Adenovirus. Sein Metabolit Ribavirin-5′-phosphat inhibiert Inosinmonophosphat (IMP)-Dehydrogenase, aber auch viele andere Wirkmechanismen sind durch experimentelle Beweise gestützt.

Virostatikum, das gegen eine Vielzahl von humanen Virusinfektionen verwendet wird, insbesondere chronischer Hepatitis C, HIV und Adenovirus. Sein Metabolit Ribavirin-5′-phosphat inhibiert Inosinmonophosphat (IMP)-Dehydrogenase.

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H341,H360FD
• pcodes: P201 - P308 + P313
• Hazard Classifications: Muta. 2 - Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable