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T8637

Thiamin-monophosphat-chlorid Dihydrat

Synonym(e):

Aneurin-monophosphat-chlorid

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Über diesen Artikel

Empirische Formel (Hill-System):
C12H18ClN4O4PS · 2H2O
CAS-Nummer:
273724-21-3
Molekulargewicht:
416.82
UNSPSC Code:
12352107
NACRES:
NA.79
PubChem Substance ID:
24900546
EC Number:
208-536-9
Beilstein/REAXYS Number:
3844977
MDL number:
MFCD00063473

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InChI

1S/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H

InChI key

GUGWNSHJDUEHNJ-UHFFFAOYSA-N

SMILES string

[Cl-].Cc1ncc(C[n+]2csc(CCOP(O)(O)=O)c2C)c(N)n1

biological source

synthetic

assay

≥99.0% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

190 °C

storage temp.

2-8°C

Quality Level

200

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Dieser Artikel
T4625T4562T1270
Thiamine monophosphate chloride dihydrate

Sigma-Aldrich

T8637

Thiamine monophosphate chloride dihydrate

Thiamine hydrochloride reagent grade, ≥99% (HPLC)

Sigma-Aldrich

T4625

Thiamine hydrochloride

Thiamine hydrochloride meets USP testing specifications

Sigma-Aldrich

T4562

Thiamine hydrochloride

Thiamine hydrochloride BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Sigma-Aldrich

T1270

Thiamine hydrochloride

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

assay

≥99.0% (HPLC)

assay

≥99% (HPLC)

assay

98.0-102.0%

assay

≥99.0% (HPLC)

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

form

powder

form

powder

form

solid

form

powder

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Application

Thiamine monophosphate chloride dihydrate has been used as a standard in high-performance liquid chromatography (HPLC) to quantify thiamine in plant exudates[1] and to evaluate its purity.[2]

Biochem/physiol Actions

Thiamine monophosphate (TMP) is used as a substrate of thiamine-phosphate kinase (EC 2.7.4.16) and a precursor of thiamine pyrophosphate (TPP). TPP is a coenzyme involved in the catabolism of sugars and amino acids.
Thiamine monophosphate (TMP) is used as a substrate of thiamine-phosphate kinase (EC 2.7.4.16) and a precursor of thiamine pyrophosphate (TPP).[3] TPP is a coenzyme involved in the catabolism of sugars and amino acids.[4] TMP acts as an intermediate in the hydrolysis of thiamine pyrophosphate to thiamine.[5]

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCM6993
BCCJ4534
BCCF7406
BCCB3210
BCBS9913

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Die Dokumentenbibliothek aufrufen

Aminoff's Neurology and General Medicine, 47(12) (2014)
Purity of standard solutions of thiamine and its phosphate esters for HPLC analysis
Ihara H, et al.
Journal of Analytical Bio-Science, 25(3) (2002)
M Héroux et al.
Neurochemical research, 20(1), 87-93 (1995-01-01)
Thiamine phosphate esters (thiamine monophosphate-TMP; thiamine diphosphate-TDP and thiamine triphosphate-TTP) were measured as their thiochrome derivatives by High Performance Liquid Chromatography in the brains of pyrithiamine-treated rats at various stages during the development of thiamine deficiency encephalopathy. Severe encephalopathy was
Structural studies of thiamin monophosphate kinase in complex with substrates and products
McCulloch KM, et al.
Biochemistry, 47(12), 3810-3821 (2008)
Maria Rapala-Kozik et al.
Plant physiology and biochemistry : PPB, 47(4), 237-242 (2009-01-27)
The pool of thiamine diphosphate (TDP), available for TDP-dependent enzymes involved in the major carbohydrate metabolic pathways, is controlled by two enzyme systems that act in the opposite directions. The thiamine pyrophosphokinase (TPK) activates thiamine into TDP and the numerous
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