SML1770

PhiKan083 hydrochloride

≥98% (HPLC)

• Synonym(e): 9-Ethyl-N-methyl-9H-Carbazole-3-methanamine hydrochloride, PK-083 hydrochloride, PK083 hydrochloride, PhiKan-083 hydrochloride
• Empirische Formel (Hill-System): C₁₆H₁₈N₂ · HCl
• CAS-Nummer: 1050480-30-2
• Molekulargewicht: 274.79
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD07168924
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CNCC1=CC2=C(C=C1)N(CC)C3=C2C=CC=C3.[H]Cl
• InChI key: IXWVUPURFWFRNE-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Mutant p53 stabilizer

PhiKan083 is a small molecule that binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319
• Sicherheitshinweise: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable