SML0029

Glycopyrroniumbromid

≥98% (HPLC)

• Synonym(e): Glycopyrrolat
• Empirische Formel (Hill-System): C₁₉H₂₈NO₃ · Br
• CAS-Nummer: 596-51-0
• Molekulargewicht: 398.33
• EG-Nummer: 209-887-0
• MDL-Nummer: MFCD00072137
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825100
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to tan
• Löslichkeit: H₂O: ≥24 mg/mL
• Ersteller: Novartis
• Lagertemp.: 2-8°C
• SMILES String: [Br-].C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)c3ccccc3
• InChI: 1S/C19H28NO3.BrH/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15;/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3;1H/q+1;/p-1
• InChIKey: VPNYRYCIDCJBOM-UHFFFAOYSA-M
• Angaben zum Gen: human ... CHRM1(1128) , CHRM3(1131)

Beschreibung

Allgemeine Beschreibung

Glycopyrrolate is a quaternary ammonium compound and it shows structural similarity with atropine.

Biochem./physiol. Wirkung

Glycopyrrolate is an anti-cholinergic drug. It is a potent controller of drooling, observed in children affected with cerebral palsy. Compared to other muscarinic antagonists, glycopyrrolate has lower CNS (central nervous system) penetration.

Glycopyrrolate is long-acting muscarinic antagonist (LAMA). It is kinetically selective muscarinic M3 receptor antagonist.

Leistungsmerkmale und Vorteile

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3