Solutions prepared at 1 mg/ml may be stored up to 8 weeks at 2 - 8°C or 20°C. This material decomposes rapidly in acidic or alkaline conditions. Solutions are most stable when prepared in degassed water and at neutral pH. Avoid repeated freeze/thaw cycles.
Fortfahren mit
SBR00067
Rifampicin Water Soluble
solubility: 50 mg/mL in water, freely soluble
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Über diesen Artikel
NACRES:
NA.76
UNSPSC Code:
51283601
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenform
solid
Quality Segment
specific activity
(Antibacterial)
sustainability
Sustainability features
solubility
water: freely soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycobacteria, viruses
mode of action
protein synthesis | interferes
storage temp.
−20°C
General description
Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC). Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease. In addition, Rifampicin is used as a selection agent for agrobacterium mediated plant transformation.
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Application
Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.
Biochem/physiol Actions
Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. Inhibits the assembly of DNA and protein into mature virus particles.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. Inhibits the assembly of DNA and protein into mature virus particles.
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| description solubility: 50 mg/mL in water, freely soluble | description Ready Made Solution, 50 mg/mL in DMSO | description suitable for plant cell culture, BioReagent, ≥95% (HPLC), powder or crystals | description ≥95% (HPLC), powder or crystals |
| antibiotic activity spectrum Gram-negative bacteria, mycobacteria, Gram-positive bacteria, viruses | antibiotic activity spectrum Gram-positive bacteria, mycobacteria, viruses, Gram-negative bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria, mycobacteria | antibiotic activity spectrum viruses, Gram-negative bacteria, Gram-positive bacteria, mycobacteria |
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form solid | form ready-to-use solution, liquid | form powder or crystals | form powder or crystals |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility water: freely soluble 50 mg/mL | solubility - | solubility - | solubility - |
Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Acute Tox. 4 Oral
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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SBR00067-- I plan to dissolve in water and aliquot in 1 ml amounts. At what temperature should the aliquotes be stored and upto how long it can be stored ( e- -20 C/-70C) After dissolving in water, how long the solution can be stored at -20 C
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