SAB2701209

Anti-ALDH1A2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): ALDH1A2, MGC26444, RALDH(II), RALDH2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human, rat, mouse
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 500-10000
• NCBI-Hinterlegungsnummer: AAH30589
• UniProt-Hinterlegungsnummer: O94788
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... ALDH1A2(8854)

Beschreibung

Immunogen

Recombinant fragment corresponding to a region within amino acids 278 and 518 of ALDH1A2 according to AAH30589

Anwendung

Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem./physiol. Wirkung

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Leistungsmerkmale und Vorteile

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Physikalische Form

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317,H412
• P-Sätze: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Gefahreneinstufungen: Aquatic Chronic 3 - Skin Sens. 1
• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable