P4279

L-α-Phosphatidylcholin

egg yolk, Type XIII-E, 100 mg/mL in ethanol, solution

• Synonym(e): 1,2-Diacyl-sn-glycero-3-phosphocholin, 3-sn-Phosphatidylcholin, L-α-Lecithin, Azolectin, PC
• CAS-Nummer: 8002-43-5
• UNSPSC Code: 51321705
• NACRES: NA.25
• Beilstein/REAXYS Number: 5209585

Eigenschaften

• biological source: egg yolk
• Quality Segment: 200
• type: Type XIII-E
• assay: ≥99% (TLC)
• form: solution
• concentration: 100 mg/mL in ethanol
• functional group: phospholipid
• lipid type: phosphoglycerides
• storage temp.: −20°C
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
• InChI key: JLPULHDHAOZNQI-ZTIMHPMXSA-N

Beschreibung

General description

Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells. This structural component of the cellular membrane is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet-activating factor, and arachidonic acid.

Application

L-α-Phosphatidylcholine has been used in differential lipid partitioning experiments of xenobiotics and natural compounds to determine trioleoylglycerol (TG) and phosphatidylcholine (PC) coefficients (KTG/PC) for partitioning of lipophilic chemicals.

Biochem/physiol Actions

Phosphatidylcholine serves as a reservoir for several lipid messengers. Phosphatidylcholine is used for the preparation of vesicle suspensions, commonly called liposomes or monolayers.

Ein großes strukturelles Phospholipid im Gehirn, das schätzungsweise 15 % der Gesamtlipide enthält; befindet sich hauptsächlich in der grauen Substanz.

Sicherheitshinweise

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Lagerklasse: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: 60.8 °F
• flash_point_c: 16 °C
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter