N3139

β-Nicotinamidadenin-Dinucleotidphosphat Hydrat

powder, BioReagent, suitable for cell culture

• Synonym(e): Triphosphopyridin-Nukleotid Natriumsalz Hydrat
• Empirische Formel (Hill-System): C₂₁H₂₇N₇NaO₁₇P₃ · xH₂O
• CAS-Nummer: 698999-85-8
• Molekulargewicht: 765.39 (anhydrous basis)
• NACRES: NA.75
• PubChem Substance ID: 24897624
• UNSPSC Code: 12352205
• MDL number: MFCD00150480
• Form: powder
• Assay: ≥98% (HPLC), ≥98% (spectrophotometric assay)
• Solubility: H₂O: 50 mg/mL

Eigenschaften

• product line: BioReagent
• Quality Segment: 200
• assay: ≥98% (HPLC), ≥98% (spectrophotometric assay)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 175-178 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• storage temp.: −20°C
• SMILES string: O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]
• InChI: 1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1
• InChI key: CYQLUFJYVTUUFN-WUEGHLCSSA-M

Beschreibung

Application

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate has been used in the purification and crystallization of CHORD–Sgt1 cytochrome b 5 reductases (CS–b5R). It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 medium for direct hepatic reprogramming using mouse embryonic fibroblasts (MEFs).

Biochem/physiol Actions

Elektronenakzeptor

Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable cofactor that participates in cellular redox reactions. It acts as a hydride-accepting coenzyme and participates in substrate oxidation reactions during metabolism.

Packaging

abgefüllt nach Gewicht des Feststoffs

Analysis Note

Meets or exceeds NRC specifications and is comparable to any commercial preparation available.

Other Notes

Dies ist die übliche Form von NADP. Nicht zu verwechseln mit 3′−NADP oder α-NADP!

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H319
• Sicherheitshinweise: P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable