I5782

Anti-Interleukin-22 Receptor, C-Terminal antibody produced in rabbit

~0,5 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-IL-22R
• MDL-Nummer: MFCD04040428
• UNSPSC-Code: 51111800

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen ~62 kDa
• Speziesreaktivität: human
• Konzentration: ~0,5 mg/mL
• Methode(n): western blot: 0.5-1 μg/mL
• UniProt-Hinterlegungsnummer: Q8N6P7
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... IL22RA1(58985)

Beschreibung

Immunogen

synthetic peptide corresponding to amino acids 560-574 of human IL-22 receptor precursor.

Biochem./physiol. Wirkung

Interleukin-22 (IL-22) belongs to the IL-10 family of T-cell associated cytokines, highly expressed by Th17 cell subset and also by cells of innate immunity system. The cellular effects of IL-22 are mediated by a heterodimeric receptor made up of IL-22 and IL-10Rβ. IL-22 signaling mediates proliferation of epithelial cells during inflammation mainly by the activation of STAT1 and STAT3 signaling.

Leistungsmerkmale und Vorteile

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Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.