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Merck

H3631

Sigma-Aldrich

Hyaluronidase aus Rindertestes

Type VI-S, lyophilized powder, 3,000-15,000 units/mg solid

Synonym(e):

Hyaluronat-4-glycanhydrolase, Hyaluronoglucosaminidase

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3000 UNITS
€ 154,00
15000 UNITS
€ 442,00
30000 UNITS
€ 1.080,00

€ 154,00


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3000 UNITS
€ 154,00
15000 UNITS
€ 442,00
30000 UNITS
€ 1.080,00

About This Item

CAS-Nummer:
EC-Nummer:
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.54

€ 154,00


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Biologische Quelle

bovine testis

Konjugat

conjugate (Glucosaminoglycan)

Typ

Type VI-S

Form

lyophilized powder

Spezifische Aktivität

3,000-15,000 units/mg solid

Mol-Gew.

~55 kDa (four subunits of 14 kDa each)

UniProt-Hinterlegungsnummer

Relevante Krankheit(en)

cancer

Lagertemp.

−20°C

Angaben zum Gen

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Biochem./physiol. Wirkung

Diese Enzyme spalten randomisiert β-N-acetylhexosamin-[1→4]-glycosidische Bindungen in Hyaluronsäure, Chondroitin und Chondroitin-Sulfaten.
Hyaluronidase baut Hyaluronan ab und wird während der Krebsprogredienz unangemessen reguliert.

Einheitendefinition

One unit will degrade 0.75 μg of the polysaccharide hyaluronic acid per minute at pH 5.35 at 37 ºC (as measured by turbidimetric absorbance (λ: 600nm) when complexed with BSA after 45 minutes).

Angaben zur Herstellung

Chromatographically purified

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Hier finden Sie alle aktuellen Versionen:

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Tongcui Ma et al.
eLife, 11 (2022-07-06)
High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously characterize many protein and glycan features of human immune cells
Dong-Ru Ho et al.
International journal of urology : official journal of the Japanese Urological Association, 18(7), 525-531 (2011-05-25)
To investigate how hyaluronic acid (HA) affects nerve growth factor (NGF) production and bladder overactivity in a cyclophosphamide (CYP)-induced cystitis rat model. Female Sprague-Dawley rats received three intermittent intraperitoneal injections of CYP (75 mg/kg) or saline. Before or after CYP injection
Tongcui Ma et al.
eLife, 9 (2020-05-27)
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infected endometrial cells by CyTOF, and
Helen M Mcgettrick et al.
Methods in molecular biology (Clifton, N.J.), 1591, 121-142 (2017-03-30)
Methods are described for analyzing adhesion and migration of isolated lymphocytes on endothelial cell monolayers which have been cocultured with different mesenchymal stromal cells, with or without additional cytokine treatment. The different cells types are grown on opposite sides of
Shared decision making, thrombotic thrombocytopenic purpura, and caplacizumab.
Senthil Sukumar et al.
American journal of hematology, 95(4), E76-E77 (2020-01-03)

Artikel

Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.

Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Protokolle

To measure hyaluronidase activity, a turbidimetric determination assay is used at 600 nm. One unit of hyaluronidase activity will cause a change in absorbance of 0.330 per minute at pH 5.35 at 37 °C.

Questions

  1. We bought this product. H3631, Batch Number: SLCH2685. Could you please provide the info on componants like, what are other componants present along with Hyaluronidase which is 3909/mg of solid (40ug, what is the remaining 940ug)?

    1 answer
    1. This product is a further purification of product H3506 and may contain some residual salts, such as sodium chloride.

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