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D8132

Dehydro-L(+)-ascorbinsäure Dimer

≥80% (enzymatic)

Synonym(e):

Bis(dehydro-L-ascorbinsäure), Bis-DHA, DHA

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Über diesen Artikel

Empirische Formel (Hill-System):
C12H12O12
CAS-Nummer:
Molekulargewicht:
348.22
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.79
Beilstein/REAXYS Number:
84277
MDL number:

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SMILES string

O1[C@@H](C(=O)C(=O)C1=O)[C@@H](O)CO

InChI

1S/C6H6O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-8H,1H2/t2-,5+/m0/s1

InChI key

SBJKKFFYIZUCET-JLAZNSOCSA-N

biological source

synthetic

assay

≥80% (enzymatic)

form

powder

color

faint beige to beige, faint brown to light brown, white to yellow

shipped in

dry ice

storage temp.

−20°C

Quality Level

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Dieser Artikel
26155695212A2218
biological source

synthetic

biological source

-

biological source

synthetic

biological source

synthetic

assay

≥80% (enzymatic)

assay

-

assay

99.0-100.5%

assay

99.0-100.5%

form

powder

form

powder

form

solid

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

General description

Dehydro-L-(+)-ascorbic acid dimer is a water soluble molecule,[1] which is produced by vitamin C in the lumen of gastrointestinal tract.[2]

Application

Dehydro-L-(+)-ascorbic acid dimer has been used to study its transformation and stability under the influence of pH, concentration and temperature.[3]

Biochem/physiol Actions

Dehydro-L-(+)-ascorbic acid dimer is used to regenerate ascorbic acid(AA). AA oxidation to dehydroascorbic acid (DHA) takes place in extracellular fluid and cells. AA acts as an antioxidant and enzyme cofactor.[2] It is used in a wide variety of applications, including cell culture. It also acts as a reducing agent, that helps reduce oxidative stress. L-Ascorbate can be regenerated from dehydroascorbic acid (DHA) by biological systems.[1]

Other Notes

Dimer in crystalline form; hydrated monomer in aqueous solution

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Gisele Monteiro et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(12), 4886-4891 (2007-03-16)
Peroxiredoxins (Prx) are widely distributed peroxidases that can be divided into 1-Cys and 2-Cys Prx groups based on the number of conserved cysteine residues that participate in their catalytical cycle. Prx have been described to be strictly dependent on thiols
Vitamin C (2017)
The physiological role of dehydroascorbic acid
Wilson JX
Febs Letters, 527(1-3), 5-9 (2002)
Sarah E Bohndiek et al.
Journal of the American Chemical Society, 133(30), 11795-11801 (2011-06-23)
Dynamic nuclear polarization (DNP) of (13)C-labeled metabolic substrates in vitro and their subsequent intravenous administration allow both the location of the hyperpolarized substrate and the dynamics of its subsequent conversion into other metabolic products to be detected in vivo. We
A Wesley Burks et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 26(4), 316-322 (2015-04-08)
Children with cow's milk allergy (CMA) are at risk for inadequate nutritional intake and growth. Dietary management of CMA, therefore, requires diets that are not only hypoallergenic but also support adequate growth in this population. This study assessed growth of

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