D7628

Dihydrouracil

powder

• Synonym(e): 5,6-Dihydro-2,4-dihydroxypyrimidine
• Empirische Formel (Hill-System): C₄H₆N₂O₂
• CAS-Nummer: 504-07-4
• Molekulargewicht: 114.10
• NACRES: NA.21
• PubChem Substance ID: 24894143
• UNSPSC Code: 12352005
• EC Number: 207-982-1
• MDL number: MFCD00006029
• Form: powder

Eigenschaften

• form: powder
• InChI: 1S/C4H6N2O2/c7-3-1-2-5-4(8)6-3/h1-2H2,(H2,5,6,7,8)
• InChI key: OIVLITBTBDPEFK-UHFFFAOYSA-N
• SMILES string: O=C1CCNC(=O)N1
• mp: 279-281 °C (lit.)
• Quality Level: 100

Beschreibung

General description

Dihydrouracil (DiHU) is a minor base found in transfer ribonucleic acid (tRNA). It is similar to uracil with the only exception that the C₅-C₆ bond is saturated. It crystallized in the monoclinic system with space group P2₁/_C. Its crystalline structure has been analyzed.[1] Its generation from L-cysteine and uracil via photochemical addition has been described.[2]

Application

Dihydrouracil has been used as a standard for ureido group in the colorimentric assay of transfer ribonucleic acid (tRNA).[3]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)