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Merck

C7017

Cholinchlorid

≥99%

Synonym(e):

(2-Hydroxyethyl)trimethylammoniumchlorid

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10 MG

€ 32,80

5 G

€ 98,80

25 G

€ 343,00

100 G

€ 1.100,00

€ 32,80


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Über diesen Artikel

Lineare Formel:
(CH3)3N(Cl)CH2CH2OH
CAS-Nummer:
Molekulargewicht:
139.62
UNSPSC Code:
50501514
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-655-4
Beilstein/REAXYS Number:
3563126
MDL number:

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Unterstützung erhalten

mp

302-305 °C (dec.) (lit.)

color

white

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

SMILES string

[Cl-].C[N+](C)(C)CCO

biological source

synthetic

assay

≥99%

form

powder

lipid type

phospholipids

Quality Level

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Dieser Artikel
C1879C752726978
biological source

synthetic

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic

assay

≥99%

assay

≥98%

assay

≥98%

assay

≥99.0% (AT)

form

powder

form

powder or crystals

form

crystals

form

powder or crystals

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

color

white

color

colorless to white

color

white

color

colorless to white

mp

302-305 °C (dec.) (lit.)

mp

302-305 °C (dec.) (lit.)

mp

302-305 °C (dec.) (lit.)

mp

302-305 °C (dec.) (lit.)

General description

Cholin-Acetyltransferase-Substrat
Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver.[1] It maintains cell structural integrity and cell signalling.[2] Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.[3]

Application

Choline chloride has been used:
  • in choline release assay[4]
  • as an endogenous agonist of sigma-1 receptors (Sig-1Rs)[5]
  • as a standard to analyse interrelationships between methionine and choline metabolism[6]

Biochem/physiol Actions

Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.

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Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Pathophysiological roles and clinical importance of biomarkers in acute coronary syndrome
Chan CP and Rainer TH
Advances in Clinical Chemistry, 59, 23-63 (2013)
Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain
Thirunavukkarasu K, et al.
Osteoarthritis and Cartilage, 25(6), 935-942 (2017)
Clinical biochemistry of domestic animals (2008)
Encyclopedia of Food Sciences and Nutrition (Second Edition) (2003)
Rumen-protected choline for dairy cows: the in situ evaluation of a commercial source and literature evaluation of effects on performance and interactions between methionine and choline metabolism
Brusemeister F and Sudekum KH
Animal Research, 55(2), 93-104 (2006)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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