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C1625

L-Canavanine

≥98% (TLC), powder, from Canavalia ensiformis

Synonym(e):

L-α-Amino-γ-(guanidinooxy)-n-butyric acid

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Über diesen Artikel

Empirische Formel (Hill-System):
C5H12N4O3
CAS-Nummer:
Molekulargewicht:
176.17
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:

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Produktname

L-Canavanine, ≥98% (TLC), powder, from Canavalia ensiformis

biological source

Canavalia ensiformis

Quality Level

assay

≥98% (TLC)

form

powder

color

white to yellow

solubility

H2O: <100 mg/mL

application(s)

detection

storage temp.

2-8°C

SMILES string

N[C@@H](CCONC(N)=N)C(O)=O

InChI

1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)/t3-/m0/s1

InChI key

FSBIGDSBMBYOPN-VKHMYHEASA-N

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Dieser Artikel
C9758G2253E1260
form

powder

form

powder

form

powder

form

powder

assay

≥98% (TLC)

assay

≥99% (TLC)

assay

≥97% (TLC)

assay

≥99% (TLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: <100 mg/mL

solubility

H2O: 100 mg/mL

solubility

-

solubility

-

color

white to yellow

color

white

color

white to off-white

color

white

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

Biochem/physiol Actions

A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Lagerklasse

11 - Combustible Solids

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Junjie Tan et al.
Nature communications, 10(1), 439-439 (2019-01-27)
RNA-guided nucleases of the CRISPR/Cas type can be repurposed as programmable nucleotide deaminases to mediate targeted nucleotide substitutions. Such base editors have enormous potential in genome editing, gene therapy and precision breeding. However, current editors suffer from limited specificity in
Karin Lanthaler et al.
BMC biology, 9, 70-70 (2011-10-26)
The uptake of drugs into cells has traditionally been considered to be predominantly via passive diffusion through the bilayer portion of the cell membrane. The recent recognition that drug uptake is mostly carrier-mediated raises the question of which drugs use
Margarita Cabrera et al.
The Journal of biological chemistry, 288(7), 5166-5175 (2012-12-25)
Transport along the endolysosomal system requires multiple fusion events at early and late endosomes. Deletion of several endosomal fusion factors, including the Vac1 tether and the Class C core vacuole/endosome tethering (CORVET) complex-specific subunits Vps3 and Vps8, results in a
Bozhena Vynnytska-Myronovska et al.
International journal of cancer, 130(9), 2164-2175 (2011-06-08)
Single amino acid arginine deprivation is a promising strategy in modern metabolic anticancer therapy. Its potency to inhibit tumor growth warrants the search for rational chemo- and radio-therapeutic approaches to be co-applied. In this report, we evaluated, for the first

Global Trade Item Number

SKUGTIN
C1625-250MG04061833467831
C1625-100MG04061833467817
C1625-1G04061833467824

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